Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTR6 | P50406 | 1/20 | 0.42 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | HRH3 | Q9Y5N1 | 6/20 | 0.38 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.38 |
| ▸ | ACHE | P22303 | 2/20 | 0.37 |
| ▸ | LTA4H | P09960 | 2/20 | 0.37 |
| ▸ | PTGS2 | P35354 | 2/20 | 0.37 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.36 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6657970 | 0.85 | ACHE (0.39) | MEN1KMT2AACHEALDH1A1SMN1; SMN2 | |
| SCHEMBL6660658 | 0.84 | CHRNB4 (0.43) | KDM4EMEN1KMT2ALTA4HPTGS2 | |
| SCHEMBL6658483 | 0.84 | MAPT (0.45) | MEN1KMT2AHRH3ACHELTA4H | |
| SCHEMBL6658813 | 0.84 | MEN1 (0.44) | KDM4EMEN1KMT2AACHEALDH1A1 | |
| SCHEMBL6661589 | 0.83 | LTA4H (0.41) | KDM4EMEN1KMT2AHRH3SIGMAR1 | |
| SCHEMBL6659951 | 0.83 | MAPT (0.40) | MEN1KMT2A | |
| SCHEMBL6658785 | 0.81 | CHRNB4 (0.44) | HRH3LTA4HPTGS2 | |
| SCHEMBL6657442 | 0.81 | MAOB (0.42) | MEN1KMT2AACHEALDH1A1 | |
| SCHEMBL6657776 | 0.81 | MAOB (0.48) | MEN1KMT2AALDH1A1 | |
| SCHEMBL6660137 | 0.80 | CYP2D6 (0.42) | KDM4EALDH1A1SMN1; SMN2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004004715-A2 | NOVEL DELTA OPIOID RECEPTOR LIGANDS | GLAXOSMITHKLINE SPA (IT) | 2004-01-15 | — | — | WO | disclosed |