Predicted protein targets (top 9)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SLC2A1 | P11166 | 1/20 | 0.36 |
| ▸ | SLC40A1 | Q9NP59 | 4/20 | 0.33 |
| ▸ | KCNH2 | Q12809 | 3/20 | 0.33 |
| ▸ | PARP1 | P09874 | 4/20 | 0.33 |
| ▸ | TNKS | O95271 | 6/20 | 0.32 |
| ▸ | TNKS2 | Q9H2K2 | 6/20 | 0.32 |
| ▸ | PARP2 | Q9UGN5 | 2/20 | 0.32 |
| ▸ | RORC | P51449 | 3/20 | 0.31 |
| ▸ | REN | P00797 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6664491 | 0.79 | HTR1A (0.35) | KCNH2 | |
| SCHEMBL6666166 | 0.78 | KCNH2 (0.39) | KCNH2 | |
| SCHEMBL6669040 | 0.77 | KCNH2 (0.45) | KCNH2 | |
| SCHEMBL6661601 | 0.74 | KCNH2 (0.45) | SLC2A1SLC40A1KCNH2 | |
| SCHEMBL6669762 | 0.72 | ALDH1A1 (0.40) | KCNH2 | |
| SCHEMBL14573148 | 0.70 | KCNH2 (0.47) | SLC2A1SLC40A1KCNH2 | |
| SCHEMBL5657093 | 0.70 | CHRNA7 (0.47) | SLC40A1PARP1PARP2 | |
| SCHEMBL5765657 | 0.65 | KCNH2 (0.47) | SLC2A1SLC40A1KCNH2 | |
| SCHEMBL5656451 | 0.64 | KDM4E (0.53) | SLC40A1 | |
| SCHEMBL14573161 | 0.63 | SLC40A1 (0.40) | SLC2A1SLC40A1KCNH2PARP1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1392686-A1 | BICYCLIC NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVES FOR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM PLC (GB) | 2004-03-03 | — | — | EP | claimed |
| WO-2002096907-A1 | BICYCLIC NITROGEN-CONTAINING HETEROCYCLIC DERIVATIVES FOR USE AS ANTIBACTERIALS | SMITHKLINE BEECHAM P.L.C. (GB) | 2002-12-05 | — | — | WO | claimed |