Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP12 | P39900 | 5/20 | 0.51 |
| ▸ | MMP13 | P45452 | 3/20 | 0.51 |
| ▸ | ALAD | P13716 | 2/20 | 0.49 |
| ▸ | MMP8 | P22894 | 2/20 | 0.48 |
| ▸ | MMP3 | P08254 | 1/20 | 0.48 |
| ▸ | MMP9 | P14780 | 1/20 | 0.48 |
| ▸ | NR4A2 | P43354 | 1/20 | 0.47 |
| ▸ | CYP46A1 | Q9Y6A2 | 1/20 | 0.47 |
| ▸ | MAPK10 | P53779 | 3/20 | 0.46 |
| ▸ | MAPK8 | P45983 | 2/20 | 0.46 |
| ▸ | MAPK9 | P45984 | 1/20 | 0.45 |
| ▸ | AXL | P30530 | 1/20 | 0.44 |
| ▸ | ABL1 | P00519 | 1/20 | 0.44 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.43 |
| ▸ | PRKACA | P17612 | 1/20 | 0.43 |
| ▸ | ROCK1 | Q13464 | 1/20 | 0.43 |
| ▸ | MMP2 | P08253 | 1/20 | 0.41 |
| ▸ | HDAC6 | Q9UBN7 | 2/20 | 0.41 |
| ▸ | HDAC1 | Q13547 | 1/20 | 0.41 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL6368823 | 0.98 | MMP12 (0.50) | MMP12MMP13ALADMMP8MMP3 | |
| SCHEMBL6882926 | 0.85 | ALAD (0.50) | MMP12MMP13ALADMMP8ABL1 | |
| SCHEMBL6881198 | 0.84 | OPRD1 (0.56) | MMP12MMP13ALADMMP8ABL1 | |
| SCHEMBL6369543 | 0.84 | ALAD (0.49) | MMP12MMP13ALADMMP8ABL1 | |
| SCHEMBL6368361 | 0.84 | ALAD (0.71) | MMP12MMP13ALADMMP8ABL1 | |
| SCHEMBL6704697 | 0.84 | ALAD (0.71) | ALADABL1KDM4EALDH1A1 | |
| SCHEMBL2326735 | 0.83 | HDAC6 (0.57) | MMP12MMP13ALADABL1HDAC6 | |
| SCHEMBL6143622 | 0.83 | ALAD (0.69) | MMP12MMP13ALADMMP8MMP3 | |
| SCHEMBL6373405 | 0.83 | MMP12 (0.52) | MMP12MMP13ALADMMP8ABL1 | |
| SCHEMBL6883103 | 0.81 | HTT (0.60) | MAPK10MAPK8CYP3A4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-20040171543-A1 | Matrix metalloproteinase inhibitors and methods for identification of lead compounds | WARNER-LAMBERT COMPANY LLC | 2004-09-02 | — | — | US | disclosed |
| WO-2004014381-A2 | MATRIX METALLOPROTEINASE INHIBITORS AND METHODS FOR IDENTIFICATION OF LEAD COMPOUNDS | WARNER-LAMBERT COMPANY LLC. (US) | 2004-02-19 | — | — | WO | disclosed |
| WO-2004014381-A2 | MATRIX METALLOPROTEINASE INHIBITORS AND METHODS FOR IDENTIFICATION OF LEAD COMPOUNDS | WARNER-LAMBERT COMPANY LLC. (US) | 2004-02-19 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040171543-A1 | Matrix metalloproteinase inhibitors and methods for identification of lead compounds | MMP13, MMP3, MMP26 | MMP12 4/4885MMP13 1/4885ALAD 2498/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.