Predicted protein targets (top 4)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | CCKBR | P32239 | 1/20 | 0.40 |
| ▸ | TP53 | P04637 | 2/20 | 0.39 |
| ▸ | MDM2 | Q00987 | 2/20 | 0.39 |
| ▸ | DAO | P14920 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6665845 | 0.88 | CCKBR (0.41) | CCKBR | |
| SCHEMBL6685148 | 0.79 | TSHR (0.43) | CCKBR | |
| SCHEMBL6678743 | 0.78 | RXRA (0.43) | CCKBR | |
| SCHEMBL6681850 | 0.77 | HDAC2 (0.42) | — | |
| SCHEMBL6683144 | 0.77 | MEN1 (0.43) | — | |
| SCHEMBL6684713 | 0.76 | TRPV1 (0.37) | CCKBR | |
| SCHEMBL6665661 | 0.76 | ALDH1A1 (0.51) | TP53 | |
| SCHEMBL6665695 | 0.71 | NR4A2 (0.43) | — | |
| SCHEMBL6684559 | 0.70 | MAPT (0.53) | TP53 | |
| SCHEMBL6831723 | 0.70 | ALDH1A1 (0.38) | — |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014388-A1 | 6,6-FUSED HETEROARYL DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |