Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.47 |
| ▸ | MAPT | P10636 | 5/20 | 0.47 |
| ▸ | MEN1 | O00255 | 4/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.47 |
| ▸ | PPARG | P37231 | 2/20 | 0.47 |
| ▸ | LMNA | P02545 | 1/20 | 0.47 |
| ▸ | TP53 | P04637 | 1/20 | 0.47 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.47 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.47 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.47 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.47 |
| ▸ | PKM | P14618 | 1/20 | 0.47 |
| ▸ | TSHR | P16473 | 1/20 | 0.47 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.47 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.47 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.47 |
| ▸ | THPO | P40225 | 1/20 | 0.47 |
| ▸ | MTOR | P42345 | 1/20 | 0.47 |
| ▸ | RORC | P51449 | 1/20 | 0.47 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6808697 | 0.89 | MAPT (0.49) | KMT2AMAPTMEN1SMN1; SMN2LMNA | |
| SCHEMBL6662272 | 0.83 | L3MBTL1 (0.51) | KMT2AMEN1LMNATP53CYP3A4 | |
| Hydrochloric Acid SCHEMBL6664266 | 0.82 | L3MBTL1 (0.50) | KMT2AMEN1LMNATP53CYP3A4 | |
| SCHEMBL6663197 | 0.82 | USP28 (0.46) | LMNATP53CFTRL3MBTL1 | |
| SCHEMBL6665172 | 0.81 | GAA (0.54) | KMT2AMAPTMEN1SMN1; SMN2CYP1A2 | |
| SCHEMBL6665641 | 0.81 | APOB (0.51) | TP53RXFP1 | |
| Hydrochloric Acid SCHEMBL6662670 | 0.80 | APOB (0.50) | TP53RXFP1 | |
| SCHEMBL6804465 | 0.76 | L3MBTL1 (0.52) | KMT2AMEN1LMNATP53CYP2C9 | |
| SCHEMBL6662843 | 0.76 | SLC2A1 (0.49) | KMT2AMEN1LMNATP53CYP2C9 | |
| Hydrochloric Acid SCHEMBL6803617 | 0.75 | L3MBTL1 (0.51) | KMT2AMEN1LMNATP53CYP2C9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1383760-A1 | BIARYLCARBOXAMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-01-28 | — | — | EP | disclosed |
| WO-2002090347-A1 | AMIDE COMPOUNDS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2002-11-14 | — | — | WO | disclosed |