Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.40 |
| ▸ | KDM5A | P29375 | 1/20 | 0.36 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.36 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.34 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.34 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.34 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.34 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.34 |
| ▸ | P2RX3 | P56373 | 2/20 | 0.33 |
| ▸ | PSEN1 | P49768 | 1/20 | 0.33 |
| ▸ | PSEN2 | P49810 | 1/20 | 0.33 |
| ▸ | APH1B | Q8WW43 | 1/20 | 0.33 |
| ▸ | NCSTN | Q92542 | 1/20 | 0.33 |
| ▸ | APH1A | Q96BI3 | 1/20 | 0.33 |
| ▸ | PSENEN | Q9NZ42 | 1/20 | 0.33 |
| ▸ | SCD | O00767 | 1/20 | 0.33 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.33 |
| ▸ | HTR1A | P08908 | 1/20 | 0.33 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6665581 | 0.91 | NNMT (0.43) | NNMTMKNK1MKNK2OPRK1KCNH2 | |
| SCHEMBL6665423 | 0.89 | NNMT (0.41) | NNMTKDM5AKDM5BMKNK1MKNK2 | |
| SCHEMBL6663534 | 0.88 | NNMT (0.41) | NNMTKDM5AKDM5BMKNK1MKNK2 | |
| SCHEMBL6681227 | 0.86 | PRKAG1 (0.39) | KDM5AKDM5B | |
| SCHEMBL6664479 | 0.86 | ROCK2 (0.40) | KDM5AKDM5BPSEN1PSEN2APH1B | |
| SCHEMBL6669268 | 0.79 | ROCK2 (0.38) | KDM5AKDM5BPSEN1PSEN2APH1B | |
| SCHEMBL6669305 | 0.79 | PRKAG1 (0.41) | NNMTKDM5AKDM5BOPRK1KCNH2 | |
| SCHEMBL6685279 | 0.79 | NR1H2 (0.38) | KDM5AKDM5B | |
| Niacinamide SCHEMBL6669309 | 0.79 | PSEN1 (0.41) | MKNK1MKNK2PSEN1PSEN2APH1B | |
| SCHEMBL6680077 | 0.78 | NR1H2 (0.40) | KDM5AKDM5BPSEN1PSEN2APH1B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014388-A1 | 6,6-FUSED HETEROARYL DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |