Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.43 |
| ▸ | P2RX3 | P56373 | 4/20 | 0.38 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.37 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.37 |
| ▸ | ROCK2 | O75116 | 3/20 | 0.37 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.36 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.36 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.36 |
| ▸ | MAOA | P21397 | 1/20 | 0.35 |
| ▸ | MAOB | P27338 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 3/20 | 0.34 |
| ▸ | NTRK1 | P04629 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6667909 | 0.91 | NNMT (0.40) | NNMTP2RX3MKNK1MKNK2OPRK1 | |
| SCHEMBL6665423 | 0.91 | NNMT (0.41) | NNMTMKNK1MKNK2OPRK1KCNH2 | |
| SCHEMBL6663534 | 0.86 | NNMT (0.41) | NNMTMKNK1MKNK2OPRK1KCNH2 | |
| SCHEMBL6664550 | 0.85 | ROCK2 (0.43) | MRGPRX4ROCK2OPRK1 | |
| SCHEMBL6663962 | 0.84 | ROCK2 (0.46) | ROCK2 | |
| SCHEMBL6664538 | 0.78 | NNMT (0.45) | NNMTP2RX3SCN9AMRGPRX4MKNK1 | |
| SCHEMBL6664479 | 0.76 | ROCK2 (0.40) | ROCK2 | |
| SCHEMBL6678968 | 0.76 | NR1H2 (0.49) | — | |
| SCHEMBL6665597 | 0.75 | ROCK2 (0.41) | ROCK2OPRK1 | |
| SCHEMBL6662847 | 0.75 | TSHR (0.41) | ROCK2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014388-A1 | 6,6-FUSED HETEROARYL DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |