Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.41 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.37 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.37 |
| ▸ | MAOB | P27338 | 1/20 | 0.37 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.37 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.36 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.36 |
| ▸ | GRM5 | P41594 | 1/20 | 0.35 |
| ▸ | NR4A2 | P43354 | 2/20 | 0.35 |
| ▸ | HPGDS | O60760 | 1/20 | 0.35 |
| ▸ | KDM5A | P29375 | 1/20 | 0.35 |
| ▸ | KDM5B | Q9UGL1 | 1/20 | 0.35 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.34 |
| ▸ | OPRD1 | P41143 | 2/20 | 0.34 |
| ▸ | CCKBR | P32239 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6665423 | 0.91 | NNMT (0.41) | NNMTMKNK1MKNK2MAOBOPRK1 | |
| SCHEMBL6664526 | 0.88 | PARP10 (0.44) | MAOBPARP10NR4A2CCKBR | |
| SCHEMBL6667909 | 0.88 | NNMT (0.40) | NNMTMKNK1MKNK2MAOBOPRK1 | |
| SCHEMBL6665581 | 0.86 | NNMT (0.43) | NNMTMKNK1MKNK2MAOBOPRK1 | |
| SCHEMBL6664500 | 0.85 | NR1H2 (0.41) | NR4A2KDM5AKDM5BCCKBR | |
| SCHEMBL6662371 | 0.85 | MAOB (0.38) | MAOBPARP10OPRK1NR4A2KDM5A | |
| Niacinamide SCHEMBL6669309 | 0.76 | PSEN1 (0.41) | MKNK1MKNK2 | |
| SCHEMBL6669379 | 0.76 | NNMT (0.43) | NNMTMKNK1MKNK2MAOBHPGDS | |
| SCHEMBL6678968 | 0.76 | NR1H2 (0.49) | CCKBR | |
| SCHEMBL6665597 | 0.75 | ROCK2 (0.41) | OPRK1KDM5AKDM5B |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014388-A1 | 6,6-FUSED HETEROARYL DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |