Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.43 |
| ▸ | NNMT | P40261 | 1/20 | 0.43 |
| ▸ | MAOA | P21397 | 1/20 | 0.42 |
| ▸ | MAOB | P27338 | 1/20 | 0.42 |
| ▸ | TP53 | P04637 | 3/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.40 |
| ▸ | CPT2 | P23786 | 1/20 | 0.40 |
| ▸ | CPT1A | P50416 | 1/20 | 0.40 |
| ▸ | CPT1B | Q92523 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.40 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 2/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 2/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 2/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 1/20 | 0.38 |
| ▸ | CASP6 | P55212 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6664538 | 0.93 | NNMT (0.45) | PTGDR2NNMTOPRM1OPRK1PRKAG1 | |
| SCHEMBL6665722 | 0.90 | NNMT (0.43) | NNMTMAOBOPRM1OPRK1KCNH2 | |
| SCHEMBL6669305 | 0.90 | PRKAG1 (0.41) | PTGDR2NNMTOPRM1OPRK1PRKAG1 | |
| SCHEMBL6665427 | 0.89 | NNMT (0.43) | PTGDR2NNMTOPRM1OPRK1PRKAG1 | |
| SCHEMBL6668559 | 0.88 | NNMT (0.41) | PTGDR2NNMTOPRM1OPRK1PRKAG1 | |
| SCHEMBL6665669 | 0.84 | CPT2 (0.43) | PTGDR2TP53SMN1; SMN2CPT2CPT1A | |
| SCHEMBL6665674 | 0.82 | P2RX3 (0.40) | PTGDR2OPRK1PRKAG1PRKAA2PRKAB1 | |
| SCHEMBL6666674 | 0.80 | KDM4C (0.42) | MAOBSMN1; SMN2OPRK1KCNH2MEN1 | |
| SCHEMBL6665535 | 0.79 | KDM5A (0.41) | PTGDR2OPRK1PRKAG1PRKAA2PRKAB1 | |
| SCHEMBL6665423 | 0.79 | NNMT (0.41) | NNMTMAOAMAOBOPRM1OPRK1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014388-A1 | 6,6-FUSED HETEROARYL DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |