Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.43 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | HCRTR1 | O43613 | 1/20 | 0.38 |
| ▸ | HCRTR2 | O43614 | 1/20 | 0.38 |
| ▸ | OPRM1 | P35372 | 2/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.38 |
| ▸ | MAOB | P27338 | 1/20 | 0.38 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.38 |
| ▸ | OPRK1 | P41145 | 2/20 | 0.37 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.37 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.37 |
| ▸ | KDM4C | Q9H3R0 | 1/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.37 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668051 | 0.90 | PTGDR2 (0.43) | NNMTOPRM1KMT2AMAOBOPRK1 | |
| SCHEMBL6665427 | 0.90 | NNMT (0.43) | NNMTKDM4EOPRM1MKNK1MKNK2 | |
| SCHEMBL6666674 | 0.89 | KDM4C (0.42) | KDM4EALDH1A1KMT2AMAOBPARP10 | |
| SCHEMBL6668559 | 0.88 | NNMT (0.41) | NNMTKDM4EOPRM1OPRK1KCNH2 | |
| SCHEMBL6669305 | 0.88 | PRKAG1 (0.41) | NNMTKDM4EOPRM1OPRK1KCNH2 | |
| SCHEMBL6664538 | 0.87 | NNMT (0.45) | NNMTOPRM1MKNK1MKNK2OPRK1 | |
| SCHEMBL6666774 | 0.87 | MAPT (0.47) | KDM4EALDH1A1KMT2AMAOBPARP10 | |
| SCHEMBL6663894 | 0.84 | ALDH1A1 (0.45) | KDM4EALDH1A1OPRM1KMT2AMAOB | |
| SCHEMBL6663534 | 0.79 | NNMT (0.41) | NNMTOPRM1MKNK1MKNK2MAOB | |
| SCHEMBL6668468 | 0.78 | KDM5A (0.41) | OPRK1KCNH2KDM4C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014388-A1 | 6,6-FUSED HETEROARYL DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |