Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NNMT | P40261 | 2/20 | 0.45 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.42 |
| ▸ | ABCB1 | P08183 | 1/20 | 0.40 |
| ▸ | OPRM1 | P35372 | 4/20 | 0.40 |
| ▸ | PTGDR2 | Q9Y5Y4 | 1/20 | 0.40 |
| ▸ | P2RX3 | P56373 | 3/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 4/20 | 0.39 |
| ▸ | PRKAG1 | P54619 | 3/20 | 0.39 |
| ▸ | PRKAA2 | P54646 | 3/20 | 0.39 |
| ▸ | PRKAB1 | Q9Y478 | 3/20 | 0.39 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 3/20 | 0.39 |
| ▸ | MRGPRX4 | Q96LA9 | 1/20 | 0.38 |
| ▸ | MKNK1 | Q9BUB5 | 1/20 | 0.38 |
| ▸ | MKNK2 | Q9HBH9 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6668051 | 0.93 | PTGDR2 (0.43) | NNMTABCB1OPRM1PTGDR2OPRK1 | |
| SCHEMBL6669305 | 0.92 | PRKAG1 (0.41) | NNMTSCN9AABCB1OPRM1PTGDR2 | |
| SCHEMBL6665427 | 0.91 | NNMT (0.43) | NNMTABCB1OPRM1PTGDR2OPRK1 | |
| SCHEMBL6668559 | 0.90 | NNMT (0.41) | NNMTABCB1OPRM1PTGDR2OPRK1 | |
| SCHEMBL6665674 | 0.89 | P2RX3 (0.40) | PTGDR2P2RX3OPRK1PRKAG1PRKAA2 | |
| SCHEMBL6665722 | 0.87 | NNMT (0.43) | NNMTOPRM1OPRK1KCNH2OPRD1 | |
| SCHEMBL6670369 | 0.83 | PRKAG1 (0.43) | PTGDR2PRKAG1PRKAA2PRKAB1 | |
| SCHEMBL6665535 | 0.81 | KDM5A (0.41) | PTGDR2OPRK1PRKAG1PRKAA2PRKAB1 | |
| SCHEMBL6668468 | 0.80 | KDM5A (0.41) | PTGDR2OPRK1PRKAG1PRKAA2PRKAB1 | |
| SCHEMBL6665581 | 0.78 | NNMT (0.43) | NNMTSCN9AABCB1OPRM1P2RX3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004014388-A1 | 6,6-FUSED HETEROARYL DERIVATIVES AS MATRIX METALLOPROTEINASE INHIBITORS | WARNER-LAMBERT COMPANY LLC (US) | 2004-02-19 | — | — | WO | disclosed |