Predicted protein targets (top 14)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MARS1 | P56192 | 5/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.41 |
| ▸ | SLC1A5 | Q15758 | 1/20 | 0.41 |
| ▸ | FNTA | P49354 | 2/20 | 0.40 |
| ▸ | FNTB | P49356 | 2/20 | 0.40 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.40 |
| ▸ | POLB | P06746 | 1/20 | 0.40 |
| ▸ | TSHR | P16473 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.39 |
| ▸ | SLC6A2 | P23975 | 1/20 | 0.39 |
| ▸ | SLC6A3 | Q01959 | 1/20 | 0.39 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL11750089 | 0.99 | MARS1 (0.42) | MARS1LMNAALDH1A1SLC1A5FNTA | |
| SCHEMBL464778 | 0.81 | ALPI (0.50) | FNTAFNTBKMT2A | |
| SCHEMBL11403740 | 0.81 | LMNA (0.50) | LMNAALDH1A1SLC1A5TDP1TSHR | |
| SCHEMBL186936 | 0.81 | LMNA (0.50) | LMNAALDH1A1SLC1A5TDP1TSHR | |
| SCHEMBL17165912 | 0.80 | MARS1 (0.39) | MARS1ALDH1A1FNTAFNTBKMT2A | |
| SCHEMBL1997086 | 0.80 | ALDH1A1 (0.45) | LMNAALDH1A1SLC1A5TDP1TSHR | |
| Hydrochloric Acid SCHEMBL6751555 | 0.80 | SLC1A5 (0.51) | LMNAALDH1A1SLC1A5TDP1POLB | |
| SCHEMBL6261937 | 0.79 | MME (0.47) | MARS1ALDH1A1TDP1POLBMAPK1 | |
| SCHEMBL534809 | 0.79 | DPP7 (0.48) | LMNAALDH1A1SLC1A5TDP1POLB | |
| SCHEMBL5084405 | 0.79 | ALDH1A1 (0.44) | LMNAALDH1A1SLC1A5TDP1POLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0986384-A4 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIV PITTSBURGH (US) | 2004-09-15 | — | — | EP | disclosed |
| EP-0986384-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 2000-03-22 | — | — | EP | disclosed |
| WO-1998050029-A1 | INHIBITORS OF PROTEIN ISOPRENYL TRANSFERASES | UNIVERSITY OF PITTSBURGH (US) | 1998-11-12 | — | — | WO | disclosed |