Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | GRIN1 | Q05586 | 4/20 | 0.40 |
| ▸ | GRIN2A | Q12879 | 4/20 | 0.40 |
| ▸ | GRIN2D | O15399 | 3/20 | 0.40 |
| ▸ | GRIN2C | Q14957 | 3/20 | 0.40 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.40 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.40 |
| ▸ | KIF11 | P52732 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.38 |
| ▸ | KCNN4 | O15554 | 2/20 | 0.36 |
| ▸ | TRPA1 | O75762 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.34 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.34 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL27997024 | 0.78 | DUT (0.41) | LMNAMAPK1KIF11ALDH1A1ALOX15 | |
| SCHEMBL28227393 | 0.78 | TRPA1 (0.40) | LMNAGRIN1GRIN2AGRIN2DGRIN2C | |
| SCHEMBL16062155 | 0.77 | ALDH1A1 (0.41) | LMNAGRIN1GRIN2AGRIN2DGRIN2C | |
| SCHEMBL6279066 | 0.77 | TSHR (0.35) | LMNAKIF11ALDH1A1ALOX15TSHR | |
| SCHEMBL8077580 | 0.76 | KIF11 (0.38) | LMNAGRIN1GRIN2AGRIN2DGRIN2C | |
| SCHEMBL9752682 | 0.76 | KIF11 (0.42) | LMNAGRIN1GRIN2AMAPK1KIF11 | |
| SCHEMBL10776485 | 0.74 | CPA3 (0.45) | MAPK1KIF11ALDH1A1TSHRCYP2C19 | |
| SCHEMBL5899999 | 0.73 | ALDH1A1 (0.39) | LMNAGRIN1GRIN2AGRIN2DGRIN2C | |
| SCHEMBL21087595 | 0.73 | TK1 (0.48) | LMNAGRIN1GRIN2AGRIN2DGRIN2C | |
| SCHEMBL4771137 | 0.73 | TK1 (0.48) | LMNAGRIN1GRIN2AGRIN2DGRIN2C |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2845587-A2 | Melanin production inhibitor | Pola Chemical Industries Inc. (JP) | 2015-03-11 | — | — | EP | disclosed |