Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NPSR1 | Q6W5P4 | 8/20 | 0.34 |
| ▸ | LMNA | P02545 | 3/20 | 0.34 |
| ▸ | TSHR | P16473 | 5/20 | 0.33 |
| ▸ | MEN1 | O00255 | 4/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 4/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.33 |
| ▸ | SMN1; SMN2 | Q16637 | 4/20 | 0.32 |
| ▸ | HTT | P42858 | 3/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | HPGD | P15428 | 1/20 | 0.30 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322443 | 0.84 | KCNN4 (0.31) | — | |
| SCHEMBL3220261 | 0.81 | AGTR1 (0.34) | — | |
| SCHEMBL2649520 | 0.80 | SMN1; SMN2 (0.41) | NPSR1LMNATSHRPOLBALDH1A1 | |
| SCHEMBL9433998 | 0.74 | ALDH1A1 (0.31) | TSHRALDH1A1P2RX7 | |
| SCHEMBL8324448 | 0.74 | P2RX7 (0.38) | TSHRMEN1KMT2APOLBALDH1A1 | |
| SCHEMBL4408728 | 0.74 | ALDH1A1 (0.50) | NPSR1LMNATSHRMEN1KMT2A | |
| SCHEMBL3939272 | 0.71 | ALDH1A1 (0.33) | NPSR1LMNATSHRMEN1KMT2A | |
| SCHEMBL10759212 | 0.71 | NPSR1 (0.31) | NPSR1 | |
| SCHEMBL8306887 | 0.69 | KCNN4 (0.44) | NPSR1LMNATSHRMEN1KMT2A | |
| SCHEMBL9434857 | 0.69 | ALDH1A1 (0.57) | LMNAMEN1KMT2AALDH1A1P2RX7 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1458393-A1 | SUBSTITUTED DIKETOPIPERAZINES AS OXYTOCIN ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2004-09-22 | — | — | EP | disclosed |
| WO-2003053443-A1 | SUBSTITUTED DIKETOPIPERAZINES AS OXYTOCIN ANTAGONISTS | GLAXO GROUP LIMITED (GB) | 2003-07-03 | — | — | WO | disclosed |