Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8322443 | 0.81 | KCNN4 (0.31) | — | |
| SCHEMBL6671874 | 0.81 | NPSR1 (0.34) | — | |
| SCHEMBL976147 | 0.77 | LMNA (0.47) | AGTR1AGTR2 | |
| SCHEMBL8323797 | 0.77 | LMNA (0.39) | AGTR1AGTR2 | |
| SCHEMBL2649520 | 0.74 | SMN1; SMN2 (0.41) | — | |
| SCHEMBL9383185 | 0.74 | AGTR1 (0.46) | AGTR1AGTR2 | |
| SCHEMBL8698703 | 0.73 | AGTR1 (0.47) | AGTR1AGTR2 | |
| SCHEMBL7388524 | 0.73 | ALDH1A1 (0.54) | — | |
| SCHEMBL3838617 | 0.72 | AGTR1 (0.41) | AGTR1AGTR2 | |
| SCHEMBL9235857 | 0.72 | MEN1 (0.42) | AGTR1AGTR2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 12 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0589665-B1 | 4,5,6,7-Tetrahydro-1H-imidazo 4,5-c pyridine-6-carboxylic acid amide derivatives as angiotensine II antagonistes | KUREHA CHEMICAL IND CO LTD (JP) | 1999-11-17 | — | — | EP | claimed |
| US-5401736-A | Angiotensis II antagonists | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1995-03-28 | — | — | US | claimed |
| EP-0589665-A2 | 4,5,6,7-Tetrahydro-1H-imidazo 4,5-c pyridine-6-carboxylic acid amide derivatives as angiotensine II antagonistes | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1994-03-30 | — | — | EP | claimed |
| US-20100029710-A1 | COMPOUNDS HAVING BOTH ANGIOTENSIN II RECEPTOR ANTAGONISM AND PPARy ACTIVATING ACTIVITIES | PFIZER PRODUCTS INC. (US) | 2010-02-04 | — | — | US | disclosed |
| EP-2125806-A1 | COMPOUNDS HAVING BOTH ANGIOTENSIN II RECEPTOR ANTAGONISM AND PPARY ACTIVATING ACTIVITIES | Pfizer Products Inc. (US) | 2009-12-02 | — | — | EP | disclosed |
| WO-2008084303-A1 | COMPOUNDS HAVING BOTH ANGIOTENSIN II RECEPTOR ANTAGONISM AND PPARY ACTIVATING ACTIVITIES | PFIZER PRODUCTS INC. (US) | 2008-07-17 | — | — | WO | disclosed |
| EP-0589665-B1 | 4,5,6,7-Tetrahydro-1H-imidazo 4,5-c pyridine-6-carboxylic acid amide derivatives as angiotensine II antagonistes | KUREHA CHEMICAL IND CO LTD (JP) | 1999-11-17 | — | — | EP | disclosed |
| US-5401736-A | Angiotensis II antagonists | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1995-03-28 | — | — | US | disclosed |
| EP-0599999-A1 | ANGIOTENSIN II RECEPTOR BLOCKING IMIDAZOLINONE DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1994-06-08 | — | — | EP | disclosed |
| WO-1994011365-A1 | SUBSTITUTED BENZIMIDAZOLES AND QUINAZOLINES AS ANTIHYPERTENSIVES | AMERICAN HOME PRODUCTS CORPORATION (US) | 1994-05-26 | — | — | WO | disclosed |
| EP-0589665-A2 | 4,5,6,7-Tetrahydro-1H-imidazo 4,5-c pyridine-6-carboxylic acid amide derivatives as angiotensine II antagonistes | KUREHA KAGAKU KOGYO KABUSHIKI KAISHA (JP) | 1994-03-30 | — | — | EP | disclosed |
| WO-1993004045-A1 | ANGIOTENSIN II RECEPTOR BLOCKING IMIDAZOLINONE DERIVATIVES | E.I. DU PONT DE NEMOURS AND COMPANY (US) | 1993-03-04 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20100029710-A1 | COMPOUNDS HAVING BOTH ANGIOTENSIN II RECEPTOR ANTAGONISM AND PPARy ACTIVATING ACTIVITIES | AGTR2, AGTR1, AGT | AGTR1 2/4885AGTR2 1/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.