Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NFE2L2 | Q16236 | 4/20 | 0.40 |
| ▸ | CA12 | O43570 | 1/20 | 0.39 |
| ▸ | CA1 | P00915 | 1/20 | 0.39 |
| ▸ | CA2 | P00918 | 1/20 | 0.39 |
| ▸ | CA4 | P22748 | 1/20 | 0.39 |
| ▸ | CA7 | P43166 | 1/20 | 0.39 |
| ▸ | CA9 | Q16790 | 1/20 | 0.39 |
| ▸ | CA14 | Q9ULX7 | 1/20 | 0.39 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | PDGFRB | P09619 | 1/20 | 0.38 |
| ▸ | PDGFRA | P16234 | 1/20 | 0.38 |
| ▸ | PKM | P14618 | 2/20 | 0.37 |
| ▸ | NPC1 | O15118 | 1/20 | 0.37 |
| ▸ | LMNA | P02545 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.37 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.37 |
| ▸ | SYK | P43405 | 1/20 | 0.36 |
| ▸ | TSHR | P16473 | 1/20 | 0.36 |
| ▸ | MEN1 | O00255 | 1/20 | 0.36 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL26454178 | 0.85 | CA12 (0.40) | CA12CA1CA2CA4CA7 | |
| SCHEMBL1837860 | 0.85 | CA12 (0.40) | NFE2L2CA12CA1CA2CA4 | |
| SCHEMBL166380 | 0.77 | NFE2L2 (0.61) | NFE2L2CA12CA1CA2CA4 | |
| SCHEMBL18472613 | 0.77 | NFE2L2 (0.61) | NFE2L2CA12CA1CA2CA4 | |
| SCHEMBL667942 | 0.76 | CA12 (0.60) | NFE2L2CA12CA1CA2CA7 | |
| SCHEMBL31240957 | 0.76 | CA12 (0.60) | NFE2L2CA12CA1CA2CA7 | |
| SCHEMBL1833359 | 0.76 | ACHE (0.60) | NPC1RAB9ASMN1; SMN2TSHRMEN1 | |
| SCHEMBL16694291 | 0.75 | KCNH2 (0.41) | KDM4ESMN1; SMN2TSHRHTTKMT2A | |
| SCHEMBL29362946 | 0.75 | MEN1 (0.46) | NFE2L2CA12CA1CA2CA4 | |
| SCHEMBL197623 | 0.75 | MEN1 (0.46) | NFE2L2CA12CA1CA2CA4 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-2321244-B1 | IMPROVED PROCESS FOR TELOMERIZATION OF BUTADIENE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-12-21 | — | — | EP | claimed |
| US-8558030-B2 | Process for telomerization of butadiene | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-10-15 | — | — | US | claimed |
| US-20110137086-A1 | PROCESS FOR TELOMERIZATION OF BUTADIENE | Dow Global Technologies LLC (Formerly known as Dow Global Technologies Inc.) (US) | 2011-06-09 | — | — | US | claimed |
| EP-2321244-A2 | AN IMPROVED PROCESS FOR TELOMERIZATION OF BUTADIENE | Dow Global Technologies LLC (US) | 2011-05-18 | — | — | EP | claimed |
| WO-2010019360-A2 | AN IMPROVED PROCESS FOR TELOMERIZATION OF BUTADIENE | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-02-18 | — | — | WO | claimed |
| EP-2321244-B1 | IMPROVED PROCESS FOR TELOMERIZATION OF BUTADIENE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2016-12-21 | — | — | EP | disclosed |
| US-8912346-B2 | Palladium phosphine complexes for the telomerization of butadiene | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-12-16 | — | — | US | disclosed |
| US-8779164-B2 | Phosphine-based catalysts useful for the telomerization of butadiene | DOW GLOBAL TECHNOLOGIES LLC (US) | 2014-07-15 | — | — | US | disclosed |
| US-8558030-B2 | Process for telomerization of butadiene | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-10-15 | — | — | US | disclosed |
| US-20130123516-A1 | NOVEL PHOSPHINE-BASED CATALYSTS USEFUL FOR THE TELOMERIZATION OF BUTADIENE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-05-16 | — | — | US | disclosed |
| EP-2431375-B1 | PALLADIUM PHOSPHINE COMPLEXES FOR THE TELOMERIZATION OF BUTADIENE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2013-05-01 | — | — | EP | disclosed |
| EP-2537582-A1 | NOVEL PHOSPHINE-BASED CATALYSTS SUITABLE FOR BUTADIENE TELOMERISATION | Dow Global Technologies LLC (US) | 2012-12-26 | — | — | EP | disclosed |
| EP-2431375-A2 | PALLADIUM PHOSPHINE COMPLEXES FOR THE TELOMERIZATION OF BUTADIENE | Dow Global Technologies LLC (US) | 2012-03-21 | — | — | EP | disclosed |
| US-20120046475-A1 | PALLADIUM PHOSPHINE COMPLEXES FOR THE TELEOMERIZATION OF BUTADIENE | DOW GLOBAL TECHNOLOGIES LLC (US) | 2012-02-23 | — | — | US | disclosed |
| US-20110137086-A1 | PROCESS FOR TELOMERIZATION OF BUTADIENE | Dow Global Technologies LLC (Formerly known as Dow Global Technologies Inc.) (US) | 2011-06-09 | — | — | US | disclosed |
| EP-2321244-A2 | AN IMPROVED PROCESS FOR TELOMERIZATION OF BUTADIENE | Dow Global Technologies LLC (US) | 2011-05-18 | — | — | EP | disclosed |
| WO-2010019360-A2 | AN IMPROVED PROCESS FOR TELOMERIZATION OF BUTADIENE | DOW GLOBAL TECHNOLOGIES INC. (US) | 2010-02-18 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20110137086-A1 | PROCESS FOR TELOMERIZATION OF BUTADIENE | HRH3, HRH4, TELO2 | NFE2L2 3224/4885CA12 4195/4885CA1 4615/4885 |
| US-20130123516-A1 | NOVEL PHOSPHINE-BASED CATALYSTS USEFUL FOR THE TELOMERIZATION OF BUTADIENE | TERT, TELO2, TPR | NFE2L2 2064/4885CA12 3667/4885CA1 4000/4885 |
| US-20120046475-A1 | PALLADIUM PHOSPHINE COMPLEXES FOR THE TELEOMERIZATION OF BUTADIENE | TTI1, TTI2, PAXBP1 | NFE2L2 2414/4885CA12 1931/4885CA1 4240/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.