Predicted protein targets (top 12)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | DPP4 | P27487 | 2/20 | 0.54 |
| ▸ | F2 | P00734 | 1/20 | 0.42 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | HTR2A | P28223 | 1/20 | 0.34 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.34 |
| ▸ | ADRA2A | P08913 | 1/20 | 0.34 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 1/20 | 0.34 |
| ▸ | HIF1A | Q16665 | 1/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL12700905 | 1.00 | DPP4 (0.54) | DPP4F2CYP3A4TDP1HTR2A | |
| SCHEMBL3022672 | 1.00 | DPP4 (0.54) | DPP4F2CYP3A4TDP1HTR2A | |
| SCHEMBL13211530 | 1.00 | DPP4 (0.54) | DPP4F2CYP3A4TDP1HTR2A | |
| SCHEMBL13211529 | 1.00 | DPP4 (0.54) | DPP4F2CYP3A4TDP1HTR2A | |
| SCHEMBL3025348 | 0.81 | ADRA2A (0.47) | DPP4F2TAAR1ADRA2AADRA2C | |
| SCHEMBL2967801 | 0.81 | ADRA2A (0.47) | DPP4F2TAAR1ADRA2AADRA2C | |
| SCHEMBL2967803 | 0.81 | ADRA2A (0.47) | DPP4F2TAAR1ADRA2AADRA2C | |
| SCHEMBL3020151 | 0.77 | DPP4 (0.52) | DPP4F2TAAR1ADRA2AADRA2C | |
| SCHEMBL18219540 | 0.76 | TAAR1 (0.39) | CYP3A4TDP1TAAR1ADRA2AADRA2C | |
| SCHEMBL4369978 | 0.76 | TAAR1 (0.37) | DPP4CYP3A4TDP1TAAR1ADRA2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 16 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2016029216-A2 | METHOD FOR PRODUCING AMIDINE DERIVATIVES | BIOCRYST PHARMACEUTICALS, INC. (US) | 2016-02-25 | — | — | WO | disclosed |
| US-8716508-B2 | Method for preparing a metal catalyst | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2014-05-06 | — | — | US | disclosed |
| US-8716508-B2 | Method for preparing a metal catalyst | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2014-05-06 | — | — | US | disclosed |
| US-8716508-B2 | Method for preparing a metal catalyst | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2014-05-06 | — | — | US | disclosed |
| US-8658825-B2 | Method for the preparation of aminophosphine ligands and their use in metal catalysts | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2014-02-25 | — | — | US | disclosed |
| US-8658825-B2 | Method for the preparation of aminophosphine ligands and their use in metal catalysts | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2014-02-25 | — | — | US | disclosed |
| US-8658825-B2 | Method for the preparation of aminophosphine ligands and their use in metal catalysts | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2014-02-25 | — | — | US | disclosed |
| US-20120046479-A1 | METHOD FOR PREPARING A METAL CATALYST | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2012-02-23 | — | — | US | disclosed |
| US-20120046479-A1 | METHOD FOR PREPARING A METAL CATALYST | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2012-02-23 | — | — | US | disclosed |
| US-20120046479-A1 | METHOD FOR PREPARING A METAL CATALYST | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2012-02-23 | — | — | US | disclosed |
| US-20100204514-A1 | METHOD FOR THE PREPARATION OF AMINOPHOSPHINE LIGANDS AND THEIR USE IN METAL CATALYSTS | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2010-08-12 | — | — | US | disclosed |
| US-20100204514-A1 | METHOD FOR THE PREPARATION OF AMINOPHOSPHINE LIGANDS AND THEIR USE IN METAL CATALYSTS | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2010-08-12 | — | — | US | disclosed |
| US-20100204514-A1 | METHOD FOR THE PREPARATION OF AMINOPHOSPHINE LIGANDS AND THEIR USE IN METAL CATALYSTS | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2010-08-12 | — | — | US | disclosed |
| WO-2010043027-A1 | METHOD FOR PREPARING A METAL CATALYST | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2010-04-22 | — | — | WO | disclosed |
| WO-2010043027-A1 | METHOD FOR PREPARING A METAL CATALYST | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2010-04-22 | — | — | WO | disclosed |
| WO-2008148202-A1 | METHOD FOR THE PREPARATION OF AMINOPHOSPHINE LIGANDS AND THEIR USE IN METAL CATALYSTS | KANATA CHEMICAL TECHNOLOGIES INC. (CA) | 2008-12-11 | — | — | WO | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (2 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120046479-A1 | METHOD FOR PREPARING A METAL CATALYST | INPP5B, DNPEP, AOC1 | DPP4 596/4885F2 858/4885CYP3A4 2744/4885 |
| US-20100204514-A1 | METHOD FOR THE PREPARATION OF AMINOPHOSPHINE LIGANDS AND THEIR USE IN METAL CATALYSTS | PNISR, PRMT9, PRMT8 | DPP4 3995/4885F2 415/4885CYP3A4 3510/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.