Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KDM4E | B2RXH2 | 4/20 | 0.63 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.63 |
| ▸ | HPGD | P15428 | 3/20 | 0.63 |
| ▸ | TDP1 | Q9NUW8 | 2/20 | 0.63 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 1/20 | 0.54 |
| ▸ | GLA | P06280 | 2/20 | 0.50 |
| ▸ | POLB | P06746 | 2/20 | 0.50 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.50 |
| ▸ | CYP2D6 | P10635 | 1/20 | 0.50 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.50 |
| ▸ | PTPN7 | P35236 | 1/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | CTSD | P07339 | 1/20 | 0.44 |
| ▸ | ALOX15 | P16050 | 1/20 | 0.43 |
| ▸ | PTGDR2 | Q9Y5Y4 | 2/20 | 0.42 |
| ▸ | OGG1 | O15527 | 1/20 | 0.42 |
| ▸ | MAPT | P10636 | 1/20 | 0.41 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL29440259 | 1.00 | KDM4E (0.63) | KDM4EALDH1A1HPGDTDP1KMT2A | |
| SCHEMBL28892041 | 0.85 | HPGD (0.47) | KDM4EALDH1A1HPGDTDP1KMT2A | |
| SCHEMBL19999165 | 0.81 | KMT2A (0.42) | KDM4EALDH1A1HPGDTDP1KMT2A | |
| SCHEMBL8582601 | 0.81 | OGG1 (0.67) | KDM4EALDH1A1HPGDTDP1KMT2A | |
| SCHEMBL21969520 | 0.81 | PTGDR2 (0.53) | KDM4EALDH1A1HPGDTDP1KMT2A | |
| SCHEMBL23512650 | 0.80 | HPGD (0.43) | KDM4EALDH1A1HPGDTDP1KMT2A | |
| SCHEMBL10051547 | 0.80 | TDP1 (0.44) | KDM4EALDH1A1HPGDTDP1KMT2A | |
| SCHEMBL29968561 | 0.79 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDTDP1KMT2A | |
| SCHEMBL28892006 | 0.79 | ALDH1A1 (0.44) | KDM4EALDH1A1HPGDTDP1KMT2A | |
| Formaldehyde SCHEMBL28892005 | 0.78 | KMT2A (0.44) | KDM4EALDH1A1HPGDTDP1KMT2A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 10 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-9513284-B2 | Pyrenyloxysulfonic acid fluorescent agents | Life Technologies Corporation (US) | 2016-12-06 | — | — | US | disclosed |
| US-20140193926-A1 | PYRENYLOXYSULFONIC ACID FLUORESCENT AGENTS | Life Technologies Corporation (US) | 2014-07-10 | — | — | US | disclosed |
| US-8614294-B2 | Pyrenyloxysulfonic acid fluorescent agents | Life Technologies Corporation (US) | 2013-12-24 | — | — | US | disclosed |
| US-20130079497-A1 | PYRENYLOXYSULFONIC ACID FLUORESCENT AGENTS | Life Technologies Corporation (US) | 2013-03-28 | — | — | US | disclosed |
| US-8268886-B2 | Pyrenyloxysulfonic acid fluorescent agents | Life Technologies Corporation (US) | 2012-09-18 | — | — | US | disclosed |
| US-20120045848-A1 | PYRENYLOXYSULFONIC ACID FLUORESCENT AGENTS | Life Technologies Corporation (US) | 2012-02-23 | — | — | US | disclosed |
| US-8039642-B2 | Pyrenyloxysulfonic acid fluorescent agents | Life Technologies Corporation (US) | 2011-10-18 | — | — | US | disclosed |
| US-20080032379-A1 | PYRENYLOXYSULFONIC ACID FLURESCENT AGENTS | INVITROGEN CORPORATION (US) | 2008-02-07 | — | — | US | disclosed |
| WO-2005064336-A1 | PYRENYLOXYSULFONIC ACID FLUORESCENT AGENTS | MOLECULAR PROBES, INC. (US) | 2005-07-14 | — | — | WO | disclosed |
| US-20050123935-A1 | Pyrenyloxysulfonic acid fluorescent agents | MOLECULAR PROBES, INC. | 2005-06-09 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20120045848-A1 | PYRENYLOXYSULFONIC ACID FLUORESCENT AGENTS | NOP56, ANXA5, ANXA6 | KDM4E 3397/4885ALDH1A1 939/4885HPGD 1450/4885 |
| US-20130079497-A1 | PYRENYLOXYSULFONIC ACID FLUORESCENT AGENTS | NOP56, ANXA5, ANXA6 | KDM4E 3397/4885ALDH1A1 939/4885HPGD 1450/4885 |
| US-20080032379-A1 | PYRENYLOXYSULFONIC ACID FLURESCENT AGENTS | NOP56, ANXA5, PFAS | KDM4E 3939/4885ALDH1A1 1070/4885HPGD 1450/4885 |
| US-20050123935-A1 | Pyrenyloxysulfonic acid fluorescent agents | NOP56, ANXA5, ANXA6 | KDM4E 3397/4885ALDH1A1 939/4885HPGD 1450/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.