Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HTT | P42858 | 5/20 | 0.34 |
| ▸ | MAPT | P10636 | 4/20 | 0.34 |
| ▸ | GAA | P10253 | 2/20 | 0.34 |
| ▸ | NPSR1 | Q6W5P4 | 2/20 | 0.34 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.34 |
| ▸ | CRHBP | P24387 | 1/20 | 0.34 |
| ▸ | CRHR2 | Q13324 | 1/20 | 0.34 |
| ▸ | NPC1 | O15118 | 2/20 | 0.34 |
| ▸ | RAB9A | P51151 | 2/20 | 0.34 |
| ▸ | JAK2 | O60674 | 1/20 | 0.34 |
| ▸ | PAX8 | Q06710 | 1/20 | 0.34 |
| ▸ | DRD2 | P14416 | 1/20 | 0.33 |
| ▸ | DRD4 | P21917 | 1/20 | 0.33 |
| ▸ | DRD3 | P35462 | 1/20 | 0.33 |
| ▸ | MTNR1A | P48039 | 1/20 | 0.32 |
| ▸ | MTNR1B | P49286 | 1/20 | 0.32 |
| ▸ | NAAA | Q02083 | 3/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.31 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.31 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8899669 | 0.79 | ANPEP (0.37) | LMNA | |
| SCHEMBL757757 | 0.73 | C3AR1 (0.39) | HTTMAPTNPC1RAB9AMTNR1A | |
| SCHEMBL757758 | 0.73 | C3AR1 (0.39) | HTTMAPTNPC1RAB9AMTNR1A | |
| SCHEMBL16318658 | 0.71 | MTNR1A (0.37) | MTNR1AMTNR1BNAAACYP2C9CYP2C19 | |
| SCHEMBL3897616 | 0.69 | NOS3 (0.34) | GAACYP1A2KMT2AMEN1SMN1; SMN2 | |
| SCHEMBL27492704 | 0.69 | ALDH1A1 (0.37) | CYP2C9CYP2C19KMT2ASMN1; SMN2ALDH1A1 | |
| SCHEMBL9390635 | 0.69 | ANPEP (0.40) | LMNA | |
| SCHEMBL8374436 | 0.69 | ANPEP (0.40) | LMNA | |
| SCHEMBL9394697 | 0.69 | ANPEP (0.40) | LMNA | |
| SCHEMBL27576022 | 0.68 | CTSK (0.39) | NAAAALDH1A1HPGDLMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004026252-A2 | GLIOMA TREATMENTS | THE REGENTS OF THE UNIVERSITY OF MICHIGAN (US) | 2004-04-01 | — | — | WO | disclosed |
| US-5859204-A | NON-ANTIGENIC, NON-IMMUNOGENIC SUPERIOR COAGULANT HUMAN/PORCINE HYBRID BY SITE DIRECTED MUTAGENESIS; HEMOPHILIA | EMORY UNIVERSITY (US) | 1999-01-12 | — | — | US | disclosed |