Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ACHE | P22303 | 3/20 | 0.34 |
| ▸ | BACE1 | P56817 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.32 |
| ▸ | ATM | Q13315 | 1/20 | 0.32 |
| ▸ | RIPK1 | Q13546 | 1/20 | 0.31 |
| ▸ | TSHR | P16473 | 2/20 | 0.31 |
| ▸ | TAAR1 | Q96RJ0 | 2/20 | 0.31 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.31 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.30 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.30 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.30 |
| ▸ | LMNA | P02545 | 1/20 | 0.30 |
| ▸ | GLA | P06280 | 1/20 | 0.30 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| Hydrochloric Acid SCHEMBL8771569 | 0.99 | ACHE (0.34) | ACHEBACE1KDM4EATMRIPK1 | |
| SCHEMBL8771747 | 0.88 | CA2 (0.39) | — | |
| SCHEMBL6676265 | 0.76 | CA2 (0.40) | KDM4ELMNAGLA | |
| SCHEMBL6675284 | 0.76 | ESRRG (0.42) | KDM4ETSHRLMNAGLA | |
| SCHEMBL6682001 | 0.75 | CA1 (0.41) | — | |
| SCHEMBL6674728 | 0.71 | MEN1 (0.36) | ATM | |
| Hydrochloric Acid SCHEMBL7242320 | 0.70 | MEN1 (0.36) | ATM | |
| SCHEMBL6675633 | 0.70 | GRM2 (0.35) | KDM4ERIPK1 | |
| SCHEMBL6676118 | 0.70 | CA2 (0.47) | KDM4ELMNAGLA | |
| SCHEMBL6681075 | 0.69 | NQO2 (0.39) | KDM4EGLA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | claimed |