SCHEMBL6674916

SCHEMBL6674916

NCCC(I)C(O)(P(=O)(O)O)P(=O)(O)O

nearest known ligand 0.41

Predicted protein targets (top 15)

geneUniProtsupporting neighboursconfidence
FDPS P14324 8/20 0.41
LMNA P02545 3/20 0.41
PDE3A Q14432 2/20 0.41
ADRB3 P13945 1/20 0.41
PDE4D Q08499 1/20 0.41
GABBR2 O75899 3/20 0.39
GABBR1 Q9UBS5 3/20 0.39
BLM P54132 2/20 0.34
CYP3A4 P08684 1/20 0.34
NFKB1 P19838 1/20 0.34
PMP22 Q01453 1/20 0.34
CYP1A2 P05177 1/20 0.32
TSHR P16473 1/20 0.32
THPO P40225 1/20 0.32
ALDH1A1 P00352 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8147759 0.86 FDPS (0.47) FDPSLMNAPDE3AADRB3PDE4D
SCHEMBL8619867 0.81 GABBR2 (0.33) FDPSLMNAPDE3AADRB3PDE4D
SCHEMBL9243663 0.74 FDPS (0.41) FDPSLMNAPDE3AADRB3PDE4D
SCHEMBL5493028 0.67 FDPS (0.45) FDPSLMNAPDE3AADRB3PDE4D
SCHEMBL5054818 0.65 ANPEP (0.44) FDPSLMNAPDE3AADRB3PDE4D
SCHEMBL8618015 0.64 LMNA (0.35) FDPSLMNA
SCHEMBL6665925 0.61 FDPS (0.50) FDPS
SCHEMBL5059579 0.61 FDPS (0.55) FDPSLMNAGABBR2GABBR1BLM
SCHEMBL5054803 0.61 FDPS (0.41) FDPSLMNAPDE3AADRB3PDE4D
Ethylenediamine SCHEMBL3636616 0.59 FDPS (0.50) FDPSLMNAPDE3AADRB3PDE4D

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20040170595-A1 Multi-arm block copolymers as drug delivery vehicles NEKTAR THERAPEUTICS AL, CORPORATION 2004-09-02 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20040170595-A1 Multi-arm block copolymers as drug delivery vehicles BCR, ABCB1, CHMP4B FDPS 2773/4885LMNA 1161/4885PDE3A 4605/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.