Predicted protein targets (top 17)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | FDPS | P14324 | 6/20 | 0.47 |
| ▸ | PDE3A | Q14432 | 2/20 | 0.44 |
| ▸ | LMNA | P02545 | 3/20 | 0.38 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.38 |
| ▸ | PDE4D | Q08499 | 1/20 | 0.38 |
| ▸ | BLM | P54132 | 2/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | NFKB1 | P19838 | 1/20 | 0.35 |
| ▸ | PMP22 | Q01453 | 1/20 | 0.35 |
| ▸ | GSR | P00390 | 1/20 | 0.35 |
| ▸ | RNPEP | Q9H4A4 | 1/20 | 0.34 |
| ▸ | GABBR2 | O75899 | 3/20 | 0.33 |
| ▸ | GABBR1 | Q9UBS5 | 3/20 | 0.33 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | THPO | P40225 | 1/20 | 0.33 |
| ▸ | CPB2 | Q96IY4 | 2/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6674916 | 0.86 | FDPS (0.41) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL5493028 | 0.71 | FDPS (0.45) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL8619867 | 0.69 | GABBR2 (0.33) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL8600008 | 0.66 | FDPS (0.60) | FDPSLMNABLMCYP3A4NFKB1 | |
| SCHEMBL9243663 | 0.65 | FDPS (0.41) | FDPSPDE3ALMNAADRB3PDE4D | |
| Putrescine SCHEMBL2541172 | 0.65 | LMNA (0.61) | FDPSPDE3ALMNABLMCYP3A4 | |
| SCHEMBL3411395 | 0.64 | FDPS (1.00) | FDPSPDE3ALMNAADRB3PDE4D | |
| SCHEMBL343017 | 0.64 | FDPS (0.61) | FDPSLMNABLMCYP3A4NFKB1 | |
| SCHEMBL9736141 | 0.64 | LAP3 (0.65) | LMNABLMCYP3A4NFKB1PMP22 | |
| SCHEMBL16005652 | 0.63 | GSR (0.39) | FDPSPDE3ALMNABLMNFKB1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6057306-A | ADMINISTERING BISPHOSPHONATES TO TREAT BONE DISEASE | NOVARTIS CORPORATION (US) | 2000-05-02 | — | — | US | claimed |