Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | AKR1B10 | O60218 | 2/20 | 0.45 |
| ▸ | AKR1B1 | P15121 | 2/20 | 0.45 |
| ▸ | HTR6 | P50406 | 3/20 | 0.43 |
| ▸ | LMNA | P02545 | 1/20 | 0.42 |
| ▸ | CA2 | P00918 | 5/20 | 0.42 |
| ▸ | CA1 | P00915 | 6/20 | 0.41 |
| ▸ | CA12 | O43570 | 2/20 | 0.41 |
| ▸ | CA4 | P22748 | 2/20 | 0.41 |
| ▸ | CA6 | P23280 | 2/20 | 0.41 |
| ▸ | CA5A | P35218 | 2/20 | 0.41 |
| ▸ | CA7 | P43166 | 2/20 | 0.41 |
| ▸ | CA9 | Q16790 | 2/20 | 0.41 |
| ▸ | CA14 | Q9ULX7 | 2/20 | 0.41 |
| ▸ | CA5B | Q9Y2D0 | 2/20 | 0.41 |
| ▸ | TYR | P14679 | 2/20 | 0.41 |
| ▸ | ABCC9 | O60706 | 1/20 | 0.41 |
| ▸ | ABCC8 | Q09428 | 1/20 | 0.41 |
| ▸ | KCNJ11 | Q14654 | 1/20 | 0.41 |
| ▸ | KCNJ8 | Q15842 | 1/20 | 0.41 |
| ▸ | HSD17B1 | P14061 | 2/20 | 0.40 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6683308 | 0.86 | CA1 (0.47) | HTR6LMNACA2CA1CA12 | |
| SCHEMBL6692553 | 0.79 | CDK1 (0.43) | CA2CA1CA12CA4CA9 | |
| SCHEMBL28042903 | 0.78 | TYR (0.61) | AKR1B10AKR1B1LMNACA1CA12 | |
| SCHEMBL21380662 | 0.76 | LMNA (0.41) | HTR6LMNACA2CA1CA12 | |
| SCHEMBL6679212 | 0.76 | LMNA (0.40) | HTR6LMNACA2CA1ALOX5 | |
| SCHEMBL27584202 | 0.75 | CA2 (0.64) | CA2CA1CA12CA4CA6 | |
| SCHEMBL8758151 | 0.75 | MET (0.56) | AKR1B10AKR1B1LMNACA2CA1 | |
| SCHEMBL28538352 | 0.74 | F2 (0.56) | LMNACA2CA1CA12CA4 | |
| SCHEMBL1754882 | 0.73 | HSD17B1 (0.56) | HTR6LMNACA2CA1CA12 | |
| SCHEMBL31146723 | 0.72 | CA2 (0.61) | HTR6LMNACA2CA12CA5A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004045610-A1 | AMINOALCOHOL DERIVATIVES AND THEIR USE AS BETA-3 ADRENERGIC RECEPTOR AGONISTS | FUJISAWA PHARMACEUTICAL CO., LTD (JP) | 2004-06-03 | — | — | WO | disclosed |