Predicted protein targets (top 19)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.36 |
| ▸ | OPRM1 | P35372 | 8/20 | 0.35 |
| ▸ | OPRD1 | P41143 | 6/20 | 0.35 |
| ▸ | OPRK1 | P41145 | 6/20 | 0.35 |
| ▸ | SLC22A1 | O15245 | 1/20 | 0.35 |
| ▸ | SLC6A4 | P31645 | 1/20 | 0.35 |
| ▸ | ADRA1A | P35348 | 1/20 | 0.35 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.35 |
| ▸ | MITF | O75030 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.34 |
| ▸ | ADORA3 | P0DMS8 | 1/20 | 0.33 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.33 |
| ▸ | ALOX5 | P09917 | 1/20 | 0.33 |
| ▸ | PRCP | P42785 | 1/20 | 0.33 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.33 |
| ▸ | GLA | P06280 | 1/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL5614157 | 0.79 | HCAR3 (0.36) | OPRM1MITFMEN1KMT2APRCP | |
| SCHEMBL28890126 | 0.77 | AKR1C1 (0.46) | OPRM1KMT2AALDH1A1 | |
| SCHEMBL6677394 | 0.73 | AKR1C1 (0.37) | SMN1; SMN2MEN1KMT2AL3MBTL1 | |
| SCHEMBL6680771 | 0.73 | AKR1C1 (0.37) | OPRM1MEN1KMT2A | |
| SCHEMBL6677414 | 0.70 | KMT2A (0.40) | MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL6677871 | 0.69 | AKR1C1 (0.34) | SLC6A4MEN1KMT2A | |
| SCHEMBL6679652 | 0.68 | CES2 (0.36) | OPRM1MEN1KMT2AALDH1A1HSD17B10 | |
| SCHEMBL6676563 | 0.67 | ATM (0.37) | SMN1; SMN2MEN1KMT2AALDH1A1 | |
| SCHEMBL6681685 | 0.66 | AKR1C1 (0.34) | MEN1KMT2A | |
| SCHEMBL29031878 | 0.64 | ALDH1A1 (0.44) | SMN1; SMN2MEN1KMT2AALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |