SCHEMBL667849

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

	Compound	similarity	top predicted	shared targets
	SCHEMBL7475478	0.82	HPGD (0.39)	ALDH1A1HPGDHTTKDM4EHSD17B10
	SCHEMBL17424932	0.81	BAZ2B (0.49)	ALDH1A1HPGDHTTKDM4EHSD17B10
	SCHEMBL7041343	0.80	MTNR1A (0.36)	ALDH1A1HPGDHTTNPC1RAB9A
	SCHEMBL9887733	0.80	KDM4E (0.36)	ALDH1A1HTTKDM4EHSD17B10NPC1
	SCHEMBL668435	0.80	KDM4E (0.43)	ALDH1A1HPGDHTTKDM4EHSD17B10
	Hydrochloric Acid SCHEMBL8876046	0.79	MTNR1A (0.35)	ALDH1A1HPGDHTTNPC1RAB9A
	SCHEMBL669425	0.79	SMN1; SMN2 (0.38)	ALDH1A1HPGDHTTKDM4EHSD17B10
	SCHEMBL27797528	0.77	HSD17B10 (0.37)	ALDH1A1HPGDHTTKDM4EHSD17B10
	SCHEMBL2427488	0.76	KDM4E (0.55)	ALDH1A1HPGDHTTKDM4EHSD17B10
	SCHEMBL7809964	0.76	KDM4E (0.53)	ALDH1A1HPGDHTTKDM4EHSD17B10

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 49 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (3 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.