SCHEMBL7475478

SCHEMBL7475478

Cc1c(C(=O)NNC(C)C(C)(C)C)ccc2c1OCCO2

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
HPGD P15428 3/20 0.39
ALDH1A1 P00352 2/20 0.37
HTT P42858 2/20 0.37
KDM4E B2RXH2 1/20 0.37
HSD17B10 Q99714 1/20 0.37
NPC1 O15118 5/20 0.36
RAB9A P51151 5/20 0.36
TP53 P04637 1/20 0.35
PKM P14618 1/20 0.35
SMN1; SMN2 Q16637 1/20 0.35
LMNA P02545 1/20 0.35
MAPT P10636 1/20 0.35
ADRA2A P08913 2/20 0.34
ADRA2C P18825 2/20 0.34
ADRA1D P25100 2/20 0.34
ADRA1A P35348 2/20 0.34
ADRA1B P35368 2/20 0.34
TAS1R3 Q7RTX0 3/20 0.33
TAS1R1 Q7RTX1 3/20 0.33
TAS1R2 Q8TE23 3/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL669425 0.84 SMN1; SMN2 (0.38) HPGDALDH1A1HTTKDM4EHSD17B10
SCHEMBL27797528 0.82 HSD17B10 (0.37) HPGDALDH1A1HTTKDM4EHSD17B10
SCHEMBL667849 0.82 ALDH1A1 (0.40) HPGDALDH1A1HTTKDM4EHSD17B10
SCHEMBL17424932 0.77 BAZ2B (0.49) HPGDALDH1A1HTTKDM4EHSD17B10
SCHEMBL668435 0.76 KDM4E (0.43) HPGDALDH1A1HTTKDM4EHSD17B10
SCHEMBL28000782 0.74 TAS1R3 (0.39) HPGDALDH1A1HTTSMN1; SMN2LMNA
SCHEMBL2427488 0.72 KDM4E (0.55) HPGDALDH1A1HTTKDM4EHSD17B10
SCHEMBL7809964 0.72 KDM4E (0.53) HPGDALDH1A1HTTKDM4EHSD17B10
SCHEMBL7479127 0.72 ABCB1 (0.39) ALDH1A1NPC1RAB9AMAPT
SCHEMBL667429 0.71 SMN1; SMN2 (0.37) HPGDALDH1A1KDM4EHSD17B10NPC1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0496342-B2 New hydrazine derivative and pesticidal composition comprising said derivative as an effective ingredient NIPPON KAYAKU KK (JP) 2002-07-24 EP disclosed
US-5530021-A AGRICULTURAL INSECTICIDES NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1996-06-25 US disclosed
US-5378726-A Insecticide, parasiticide NIPPON KAYAKU KABUSHIKI KAISHA (JP) 1995-01-03 US disclosed