SCHEMBL6679575

SCHEMBL6679575

C#Cc1ccccc1CS

nearest known ligand 0.50

Predicted protein targets (top 6)

geneUniProtsupporting neighboursconfidence
IDO1 P14902 2/20 0.50
CYP1A1 P04798 1/20 0.33
CYP1A2 P05177 1/20 0.33
CYP1B1 Q16678 1/20 0.33
PYCR1 P32322 1/20 0.32
PNMT P11086 1/20 0.30

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL9862093 0.80 HSPA5 (0.40) IDO1CYP1A1CYP1A2CYP1B1PYCR1
SCHEMBL4170188 0.78 TRPA1 (0.36) IDO1CYP1A1CYP1A2CYP1B1PYCR1
SCHEMBL7061714 0.76 ALDH1A1 (0.38) IDO1CYP1A1CYP1A2CYP1B1PYCR1
SCHEMBL4953056 0.76 GABRA1 (0.46) PYCR1
SCHEMBL28884063 0.76 CYP1A1 (0.33) IDO1CYP1A1CYP1A2CYP1B1PYCR1
SCHEMBL3973809 0.76 PNMT (0.50) CYP1A1CYP1A2CYP1B1PYCR1PNMT
SCHEMBL1253891 0.76 CYP1A1 (0.33) IDO1CYP1A1CYP1A2CYP1B1PYCR1
SCHEMBL149728 0.76 APOBEC3G (0.43) CYP1A1CYP1A2CYP1B1PYCR1
SCHEMBL20838091 0.76 CYP1A1 (0.33) IDO1CYP1A1CYP1A2CYP1B1PYCR1
SCHEMBL29456692 0.76 GABRA1 (0.46) PYCR1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-0759457-B2 Weather and soiling-resistant silicone-containing coating composition SHINETSU CHEMICAL CO (JP) 2004-06-16 EP claimed
EP-0759457-B1 Weather and soiling-resistant silicone-containing coating composition SHINETSU CHEMICAL CO (JP) 2001-06-13 EP claimed
CN-114437138-A Metal complex and organic electroluminescent device 上海八亿时空先进材料有限公司 2022-05-06 CN disclosed