SCHEMBL667989

SCHEMBL667989

CC1(COc2ccccc2)CO1

nearest known ligand 0.41

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
KCNA3 P22001 1/20 0.41
TDP1 Q9NUW8 1/20 0.41
LTA4H P09960 2/20 0.39
HTR1A P08908 1/20 0.39
HTR1B P28222 2/20 0.38
LMNA P02545 1/20 0.38
HTR1D P28221 1/20 0.38
TAAR1 Q96RJ0 1/20 0.38
ALDH1A1 P00352 1/20 0.38
RECQL P46063 1/20 0.38
MTNR1A P48039 1/20 0.37
MTNR1B P49286 1/20 0.37
PKM P14618 1/20 0.36
ALOX15 P16050 1/20 0.36
ADRA1A P35348 1/20 0.36
CHRNB2 P17787 1/20 0.36
CHRNB4 P30926 1/20 0.36
CHRNA3 P32297 1/20 0.36
CHRNA7 P36544 1/20 0.36
CHRNA4 P43681 1/20 0.36

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL19091769 1.00 KCNA3 (0.41) KCNA3TDP1LTA4HHTR1AHTR1B
SCHEMBL1228633 0.86 PTGS1 (0.51) LMNAALDH1A1
SCHEMBL27527783 0.85 TDP1 (0.39) KCNA3TDP1LTA4HHTR1AHTR1B
SCHEMBL4461068 0.84 DRD2 (0.40) LMNAALDH1A1KCNH2
SCHEMBL2836200 0.84 ALDH1A1 (0.36) LMNAALDH1A1
SCHEMBL9990086 0.82 L3MBTL1 (0.54) LTA4HLMNAALDH1A1
SCHEMBL2312518 0.81 DRD2 (0.40) TDP1LTA4HLMNAALDH1A1RECQL
SCHEMBL9774630 0.81 PLA2G7 (0.40) TDP1ALDH1A1
SCHEMBL1227914 0.81 APP (0.42)
SCHEMBL4455696 0.80 DRD2 (0.44) TDP1LMNAALDH1A1ALOX15

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 60 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
CN-108555012-A A kind of processing heavy metal pollution of soil object band rotation drying system 徐州工程学院 2018-09-21 CN claimed
EP-4606902-A1 PREPARATION OF ENANTIO-SPECIFIC EPOXIDES Vilnius University (LT) 2025-08-27 EP disclosed
CN-120129725-A Two-component powder coating composition with separate catalyst system 湛新荷兰有限公司 2025-06-10 CN disclosed
CN-117813356-A Powder coating composition blend 湛新荷兰有限公司 2024-04-02 CN disclosed
CN-117730112-A Powder coating and crystalline donor and/or acceptor 湛新荷兰有限公司 2024-03-19 CN disclosed
CN-117440979-A Powder coating and crystallization precursor catalyst 湛新荷兰有限公司 2024-01-23 CN disclosed
CN-111630081-B Powder coating composition 湛新荷兰有限公司 2023-10-31 CN disclosed
CN-109476773-B Curable composition, cured product, and method for producing cured product 株式会社艾迪科 2022-05-13 CN disclosed
CN-110869467-B Composition, cured product, and method for producing cured product 株式会社艾迪科 2022-05-10 CN disclosed
US-20210403445-A1 SYSTEMS AND METHODS FOR REGIOSELECTIVE CARBONYLATION OF 2,2-DISUBSTITUTED EPOXIDES CORNELL UNIVERSITY 2021-12-30 US disclosed
US-6037405-A NOVOLAK RESIN MODIFIED WITH HYDROXYALKYLESTER GROUPS; PAINTS, COATINGS; STORAGE STABILITY, ANTIAGGLOMERANTS SAKATA INX CORP. (JP) 2000-03-14 US disclosed
US-6022894-A Method of using calcilytic compounds NPS PHARMACEUTICALS, INC. (US) 2000-02-08 US disclosed
EP-0781820-B1 Pigment dispersion and offset printing ink composition using the same SAKATA INX CORP (JP) 1999-09-08 EP disclosed
EP-0901459-A1 CALCILYTIC COMPOUNDS NPS PHARMACEUTICALS, INC. (US) 1999-03-17 EP disclosed
US-5847028-A Pigment dispersion and offset printing ink composition using the same SAKATA INX CORP. (JP) 1998-12-08 US disclosed
WO-1997037967-A1 CALCILYTIC COMPOUNDS NPS PHARMACEUTICALS, INC. (US) 1997-10-16 WO disclosed
EP-0781820-A2 Pigment dispersion and offset printing ink composition using the same SAKATA INX CORPORATION (JP) 1997-07-02 EP disclosed
EP-0094436-B1 N-GLYCIDYL-SUBSTITUTED AMIDE COMPOUNDS MITSUI TOATSU CHEMICALS, Inc. (JP) 1988-03-30 EP disclosed
US-4309441-A HYPOTENSIVE AGENTS MERCK PATENT GESELLSCHAFT MIT BESCHRANKTER HAFTUNG (DE) 1982-01-05 US disclosed
US-4259236-A COLORFAST RED SHADES ON POLYESTERS CIBA-GEIGY CORPORATION (US) 1981-03-31 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20210403445-A1 SYSTEMS AND METHODS FOR REGIOSELECTIVE CARBONYLATION OF 2,2-DISUBSTITUTED EPOXIDES LTC4S, LSS, CYCS KCNA3 2823/4885TDP1 4314/4885LTA4H 59/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.