Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PPARG | P37231 | 2/20 | 0.48 |
| ▸ | PPARD | Q03181 | 1/20 | 0.48 |
| ▸ | PPARA | Q07869 | 1/20 | 0.48 |
| ▸ | NAAA | Q02083 | 2/20 | 0.45 |
| ▸ | NLRP3 | Q96P20 | 1/20 | 0.43 |
| ▸ | PRKCA | P17252 | 6/20 | 0.43 |
| ▸ | LMNA | P02545 | 2/20 | 0.42 |
| ▸ | DNTT | P04053 | 1/20 | 0.42 |
| ▸ | POLM | Q9NP87 | 1/20 | 0.41 |
| ▸ | POLK | Q9UBT6 | 1/20 | 0.41 |
| ▸ | POLL | Q9UGP5 | 1/20 | 0.41 |
| ▸ | POLH | Q9Y253 | 1/20 | 0.41 |
| ▸ | DGKA | P23743 | 1/20 | 0.41 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6676379 | 1.00 | PPARG (0.48) | PPARGPPARDPPARANAAANLRP3 | |
| SCHEMBL6675746 | 1.00 | PPARG (0.48) | PPARGPPARDPPARANAAANLRP3 | |
| SCHEMBL6675203 | 0.98 | PPARG (0.46) | PPARGPPARDPPARANAAANLRP3 | |
| SCHEMBL6676582 | 0.94 | PPARG (0.41) | PPARGPPARDPPARANAAANLRP3 | |
| SCHEMBL6680654 | 0.81 | ALDH1A1 (0.41) | PPARGPPARDPPARADNTT | |
| SCHEMBL6676518 | 0.78 | TRPA1 (0.35) | PPARGPPARDPPARALMNADNTT | |
| SCHEMBL2239670 | 0.73 | DGKA (0.52) | NAAAPRKCALMNADGKA | |
| SCHEMBL5080113 | 0.72 | NAAA (0.50) | NAAAPRKCALMNADGKA | |
| SCHEMBL5080133 | 0.72 | NAAA (0.50) | NAAAPRKCALMNADGKA | |
| SCHEMBL5079233 | 0.72 | NAAA (0.50) | NAAAPRKCALMNADGKA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1112742-B1 | REMEDIES OR PREVENTIVES CONTAINING CYCLOPENTENONE COMPOUNDS AS THE ACTIVE INGREDIENT | TAKARA BIO INC (JP) | 2004-11-03 | — | — | EP | claimed |
| EP-1112742-B1 | REMEDIES OR PREVENTIVES CONTAINING CYCLOPENTENONE COMPOUNDS AS THE ACTIVE INGREDIENT | TAKARA BIO INC (JP) | 2004-11-03 | — | — | EP | disclosed |