Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PGK1 | P00558 | 3/20 | 0.39 |
| ▸ | PGK2 | P07205 | 3/20 | 0.39 |
| ▸ | MEN1 | O00255 | 2/20 | 0.36 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.36 |
| ▸ | CES2 | O00748 | 1/20 | 0.34 |
| ▸ | MGLL | Q99685 | 1/20 | 0.34 |
| ▸ | NR1H2 | P55055 | 2/20 | 0.33 |
| ▸ | NR1H3 | Q13133 | 2/20 | 0.33 |
| ▸ | PNMT | P11086 | 1/20 | 0.33 |
| ▸ | ACP3 | P15309 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.33 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.33 |
| ▸ | IDH2 | P48735 | 1/20 | 0.33 |
| ▸ | TAAR1 | Q96RJ0 | 1/20 | 0.32 |
| ▸ | HTR3E | A5X5Y0 | 1/20 | 0.32 |
| ▸ | HTR3B | O95264 | 1/20 | 0.32 |
| ▸ | HTR3A | P46098 | 1/20 | 0.32 |
| ▸ | HTR3D | Q70Z44 | 1/20 | 0.32 |
| ▸ | HTR3C | Q8WXA8 | 1/20 | 0.32 |
| ▸ | IDO1 | P14902 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6680835 | 0.85 | ALDH1A1 (0.42) | MEN1KMT2ANR1H2NR1H3TSHR | |
| SCHEMBL6680836 | 0.82 | NR1H2 (0.41) | PGK1PGK2NR1H2NR1H3ESR1 | |
| SCHEMBL24087499 | 0.73 | MLYCD (0.42) | MEN1KMT2ANR1H2NR1H3TSHR | |
| SCHEMBL30788987 | 0.73 | CA1 (0.37) | NR1H2NR1H3ESR1ESR2 | |
| SCHEMBL6980412 | 0.72 | CES2 (0.44) | MEN1KMT2ACES2MGLLPNMT | |
| SCHEMBL14874502 | 0.70 | PGK1 (0.33) | PGK1PGK2MEN1KMT2APNMT | |
| SCHEMBL12350199 | 0.67 | TSHR (0.52) | MEN1KMT2APNMTTSHRMAPK1 | |
| SCHEMBL5476864 | 0.67 | CTSK (0.41) | MEN1KMT2ACES2MGLLPNMT | |
| SCHEMBL27491062 | 0.67 | TSHR (0.46) | PGK1PGK2MEN1KMT2ATSHR | |
| SCHEMBL2015017 | 0.67 | TSHR (0.46) | PGK1PGK2MEN1KMT2ATSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 6 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1084860-B1 | Thermochromic microencapsulated pigments | PILOT INK CO LTD (JP) | 2004-11-24 | — | — | EP | disclosed |
| EP-0908501-B1 | Reversible thermochromic composition | PILOT INK CO LTD (JP) | 2003-07-09 | — | — | EP | disclosed |
| US-6494950-B1 | FOUR ESSENTIAL COMPONENTS (A) AN ELECTRON-DONATING CHROMATIC ORGANIC COMPOUND, (B) AN ELECTRON-ACCEPTING COMPOUND, (C) A REACTION MEDIUM DETERMINING THE TEMPERATURES AT WHICH THE COLOR REACTIONS OF COMPONENT (A) WITH COMPONENT (B) TAKE | THE PILOT INK CO., LTD. (JP) | 2002-12-17 | — | — | US | disclosed |
| EP-1084860-A2 | Thermochromic microencapsulated pigments | THE PILOT INK CO., LTD. (JP) | 2001-03-21 | — | — | EP | disclosed |
| US-6048387-A | SPECIFIED DIAZARHODAMINE LACTONE DERIVATIVE AS AN ELECTRON-DONATING COLOR-DEVELOPING ORGANIC COMPOUND | THE PILOT INK CO., LTD. (JP) | 2000-04-11 | — | — | US | disclosed |
| EP-0908501-A1 | Reversible thermochromic composition | THE PILOT INK CO., LTD. (JP) | 1999-04-14 | — | — | EP | disclosed |