SCHEMBL6680835

SCHEMBL6680835

OCCC(c1ccccc1)(C(F)(F)F)C(F)(F)F

nearest known ligand 0.42

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
ALDH1A1 P00352 2/20 0.42
TSHR P16473 1/20 0.42
PTPN1 P18031 1/20 0.39
NR1H2 P55055 7/20 0.37
NR1H3 Q13133 7/20 0.37
MEN1 O00255 2/20 0.37
KMT2A Q03164 2/20 0.37
S1PR4 O95977 1/20 0.37
LMNA P02545 1/20 0.37
MAPT P10636 1/20 0.37
S1PR1 P21453 1/20 0.37
NPSR1 Q6W5P4 1/20 0.37
TDP1 Q9NUW8 1/20 0.34
CYP1A2 P05177 1/20 0.34
CYP2C9 P11712 1/20 0.34
CYP2C19 P33261 1/20 0.34
SMN1; SMN2 Q16637 2/20 0.33
KIF11 P52732 1/20 0.33
CA1 P00915 1/20 0.33
CA2 P00918 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6680836 0.89 NR1H2 (0.41) NR1H2NR1H3
SCHEMBL6681599 0.85 PGK1 (0.39) TSHRNR1H2NR1H3MEN1KMT2A
SCHEMBL4982671 0.82 TSHR (0.46) ALDH1A1TSHRPTPN1NR1H2NR1H3
SCHEMBL30788987 0.79 CA1 (0.37) NR1H2NR1H3LMNAMAPTNPSR1
SCHEMBL24087499 0.79 MLYCD (0.42) TSHRNR1H2NR1H3MEN1KMT2A
SCHEMBL2015017 0.77 TSHR (0.46) ALDH1A1TSHRPTPN1MEN1KMT2A
SCHEMBL27491062 0.77 TSHR (0.46) ALDH1A1TSHRPTPN1MEN1KMT2A
SCHEMBL15043735 0.75 ALDH1A1 (0.39) ALDH1A1TSHRPTPN1NR1H2NR1H3
SCHEMBL20588187 0.75 EPHX2 (0.43) MEN1KMT2ANPSR1SMN1; SMN2KIF11
SCHEMBL10494089 0.74 ALDH1A1 (0.42) ALDH1A1TSHRPTPN1MEN1KMT2A

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 7 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20260034094-A1 COMPOSITIONS AND METHODS FOR INDUCING FERROPTOSIS KOJIN THERAPEUTICS INC (US) 2026-02-05 US disclosed
EP-1084860-B1 Thermochromic microencapsulated pigments PILOT INK CO LTD (JP) 2004-11-24 EP disclosed
EP-0908501-B1 Reversible thermochromic composition PILOT INK CO LTD (JP) 2003-07-09 EP disclosed
US-6494950-B1 FOUR ESSENTIAL COMPONENTS (A) AN ELECTRON-DONATING CHROMATIC ORGANIC COMPOUND, (B) AN ELECTRON-ACCEPTING COMPOUND, (C) A REACTION MEDIUM DETERMINING THE TEMPERATURES AT WHICH THE COLOR REACTIONS OF COMPONENT (A) WITH COMPONENT (B) TAKE THE PILOT INK CO., LTD. (JP) 2002-12-17 US disclosed
EP-1084860-A2 Thermochromic microencapsulated pigments THE PILOT INK CO., LTD. (JP) 2001-03-21 EP disclosed
US-6048387-A SPECIFIED DIAZARHODAMINE LACTONE DERIVATIVE AS AN ELECTRON-DONATING COLOR-DEVELOPING ORGANIC COMPOUND THE PILOT INK CO., LTD. (JP) 2000-04-11 US disclosed
EP-0908501-A1 Reversible thermochromic composition THE PILOT INK CO., LTD. (JP) 1999-04-14 EP disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20260034094-A1 COMPOSITIONS AND METHODS FOR INDUCING FERROPTOSIS AIFM2, GPX4, HMOX1 ALDH1A1 3274/4885TSHR 699/4885PTPN1 3299/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.