Predicted protein targets (top 2)
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6681635 | 1.00 | MMP2 (0.50) | MMP2MMP12 | |
| SCHEMBL6677174 | 0.86 | MMP12 (0.61) | MMP2MMP12 | |
| SCHEMBL4556349 | 0.82 | ADAM17 (0.50) | MMP2MMP12 | |
| SCHEMBL4556352 | 0.82 | ADAM17 (0.50) | MMP2MMP12 | |
| SCHEMBL4059802 | 0.82 | ADAM17 (0.50) | MMP2MMP12 | |
| SCHEMBL6681651 | 0.81 | MMP12 (0.47) | MMP2MMP12 | |
| SCHEMBL4556187 | 0.78 | ADAM17 (0.57) | MMP2MMP12 | |
| SCHEMBL6700679 | 0.75 | MMP12 (0.42) | MMP2MMP12 | |
| SCHEMBL4050505 | 0.72 | MMP2 (0.61) | MMP2 | |
| SCHEMBL6100999 | 0.71 | MMP13 (0.63) | MMP2MMP12 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1397137-A4 | HYDANTION DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | BRISTOL MYERS SQUIBB CO (US) | 2004-10-13 | — | — | EP | claimed |
| EP-1397137-A1 | HYDANTION DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2004-03-17 | — | — | EP | claimed |
| WO-2002096426-A1 | HYDANTION DERIVATIVES AS INHIBITORS OF MATRIX METALLOPROTEINASES | BRISTOL-MYERS SQUIBB COMPANY (US) | 2002-12-05 | — | — | WO | claimed |