Predicted protein targets (top 15)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | TLR8 | Q9NR97 | 1/20 | 0.47 |
| ▸ | SMO | Q99835 | 8/20 | 0.46 |
| ▸ | KIF11 | P52732 | 1/20 | 0.45 |
| ▸ | PTGS1 | P23219 | 1/20 | 0.44 |
| ▸ | MTTP | P55157 | 5/20 | 0.43 |
| ▸ | APOB | P04114 | 4/20 | 0.43 |
| ▸ | P2RX1 | P51575 | 2/20 | 0.43 |
| ▸ | RUVBL1 | Q9Y265 | 1/20 | 0.43 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.43 |
| ▸ | MAPT | P10636 | 1/20 | 0.43 |
| ▸ | HPGD | P15428 | 1/20 | 0.43 |
| ▸ | NPC1 | O15118 | 1/20 | 0.42 |
| ▸ | RAB9A | P51151 | 1/20 | 0.42 |
| ▸ | POLB | P06746 | 1/20 | 0.42 |
| ▸ | GAA | P10253 | 1/20 | 0.42 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6678296 | 0.80 | POLB (0.46) | ALDH1A1MAPTHPGDPOLBGAA | |
| SCHEMBL2990416 | 0.73 | MTTP (0.67) | SMOMTTPAPOB | |
| SCHEMBL6027598 | 0.73 | RXRA (0.55) | ALDH1A1MAPTHPGD | |
| SCHEMBL7079762 | 0.72 | RXFP1 (0.73) | — | |
| SCHEMBL3290068 | 0.71 | EPHX2 (0.45) | SMOMTTPAPOB | |
| SCHEMBL4197692 | 0.71 | MTTP (0.49) | SMOMTTPAPOBMAPT | |
| SCHEMBL7083823 | 0.69 | POLB (0.61) | KIF11ALDH1A1HPGDNPC1RAB9A | |
| SCHEMBL3971988 | 0.69 | RXFP1 (0.62) | P2RX1MAPTHPGDNPC1RAB9A | |
| SCHEMBL4997367 | 0.68 | PTGS1 (0.61) | PTGS1P2RX1MAPTRAB9AGAA | |
| SCHEMBL28688539 | 0.68 | MEN1 (0.64) | ALDH1A1HPGDNPC1RAB9APOLB |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1472226-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2004-11-03 | — | — | EP | disclosed |
| WO-2003045921-A1 | HETEROCYCLIC AMIDE COMPOUNDS AS APOLIPOPROTEIN B INHIBITORS | FUJISAWA PHARMACEUTICAL CO., LTD. (JP) | 2003-06-05 | — | — | WO | disclosed |