Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP1 | P03956 | 5/20 | 0.48 |
| ▸ | LTA4H | P09960 | 2/20 | 0.45 |
| ▸ | MMP13 | P45452 | 4/20 | 0.42 |
| ▸ | MMP2 | P08253 | 3/20 | 0.42 |
| ▸ | MMP9 | P14780 | 2/20 | 0.42 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.42 |
| ▸ | NR3C1 | P04150 | 1/20 | 0.39 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.39 |
| ▸ | MEP1B | Q16820 | 1/20 | 0.39 |
| ▸ | SCN9A | Q15858 | 1/20 | 0.38 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.38 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.38 |
| ▸ | TAS2R14 | Q9NYV8 | 1/20 | 0.38 |
| ▸ | CETP | P11597 | 1/20 | 0.37 |
| ▸ | MMP8 | P22894 | 1/20 | 0.37 |
| ▸ | MMP14 | P50281 | 1/20 | 0.37 |
| ▸ | MMP16 | P51512 | 1/20 | 0.37 |
| ▸ | MMP7 | P09237 | 1/20 | 0.37 |
| ▸ | RAB9A | P51151 | 1/20 | 0.37 |
| ▸ | CACNA1H | O95180 | 1/20 | 0.37 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL7421019 | 0.88 | SMN1; SMN2 (0.46) | MMP1LTA4HMMP13MMP2MMP9 | |
| SCHEMBL231737 | 0.81 | MMP1 (0.55) | MMP1LTA4HMMP13MMP2MMP9 | |
| SCHEMBL6809658 | 0.70 | MMP13 (0.50) | MMP1LTA4HMMP13MMP2MMP9 | |
| SCHEMBL7344819 | 0.70 | MMP1 (0.43) | MMP1MMP13MMP2MMP9MEP1B | |
| SCHEMBL6817940 | 0.70 | MMP1 (0.48) | MMP1MMP13MMP2MMP9NR3C1 | |
| SCHEMBL27839121 | 0.69 | MMP1 (0.64) | MMP1LTA4HMMP13MMP2MMP9 | |
| SCHEMBL27856906 | 0.69 | MMP1 (0.67) | MMP1LTA4HMMP13MMP2MMP9 | |
| SCHEMBL1133869 | 0.69 | MMP8 (0.65) | MMP1MMP13MMP2MMP9FFAR1 | |
| SCHEMBL5243658 | 0.68 | MMP1 (0.56) | MMP1LTA4HMMP13MMP2MMP9 | |
| SCHEMBL6903460 | 0.68 | MMP1 (0.53) | MMP1LTA4HMMP13MMP2MMP9 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 17 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1003720-B1 | ARYLOXYARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER PROD INC (US) | 2004-03-31 | — | — | EP | claimed |
| US-6214872-B1 | ANTIARTHRITIC AND ANTICARCINOGENIC AGENTS | PFIZER INC. | 2001-04-10 | — | — | US | claimed |
| EP-1003720-A1 | ARYLOXYARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | Pfizer Products Inc. (US) | 2000-05-31 | — | — | EP | claimed |
| WO-1999007675-A1 | ARYLOXYARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER PRODUCTS INC. (US) | 1999-02-18 | — | — | WO | claimed |
| EP-3137460-A1 | CYCLOALKYL-LINKED DIHETEROCYCLE DERIVATIVES | Pfizer Inc. (US) | 2017-03-08 | — | — | EP | disclosed |
| WO-2015166373-A1 | CYCLOALKYL-LINKED DIHETEROCYCLE DERIVATIVES | PFIZER INC. (US) | 2015-11-05 | — | — | WO | disclosed |
| CN-102807617-A | Antibodies to M-CSF | WARNER LAMBERT CO | 2012-12-05 | — | — | CN | disclosed |
| CN-1835975-B | Modified human IGF-1R antibodies | PFIZER PROD INC | 2012-11-21 | — | — | CN | disclosed |
| CN-101128484-B | Compositions comprising anti-IGF-1 receptor antibodies and methods for obtaining same | AMGEN INC | 2012-09-26 | — | — | CN | disclosed |
| CN-1863817-B | Antibodies to M-CSF | WARNER LAMBERT CO | 2012-07-04 | — | — | CN | disclosed |
| CN-101018780-B | Pyrazole-substituted aminoheteroaryl compounds as protein kinase inhibitors | PFIZER | 2012-01-11 | — | — | CN | disclosed |
| WO-2004083248-A9 | ANTIBODIES TO IGF-I RECEPTOR FOR THE TREATMENT OF CANCERS | PHARMACIA CORP (US) | 2004-12-29 | — | — | WO | disclosed |
| EP-1415984-A1 | Aryloxyarylsulfonylamino hydroxamic acid derivatives | Pfizer Products Inc. (US) | 2004-05-06 | — | — | EP | disclosed |
| EP-1003720-B1 | ARYLOXYARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER PROD INC (US) | 2004-03-31 | — | — | EP | disclosed |
| US-6214872-B1 | ANTIARTHRITIC AND ANTICARCINOGENIC AGENTS | PFIZER INC. | 2001-04-10 | — | — | US | disclosed |
| EP-1003720-A1 | ARYLOXYARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | Pfizer Products Inc. (US) | 2000-05-31 | — | — | EP | disclosed |
| WO-1999007675-A1 | ARYLOXYARYLSULFONYLAMINO HYDROXAMIC ACID DERIVATIVES | PFIZER PRODUCTS INC. (US) | 1999-02-18 | — | — | WO | disclosed |