Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 4/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.41 |
| ▸ | NPC1 | O15118 | 2/20 | 0.41 |
| ▸ | MAPT | P10636 | 2/20 | 0.41 |
| ▸ | RAB9A | P51151 | 1/20 | 0.41 |
| ▸ | ALDH1A1 | P00352 | 4/20 | 0.41 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.41 |
| ▸ | TP53 | P04637 | 1/20 | 0.41 |
| ▸ | ADRB2 | P07550 | 1/20 | 0.40 |
| ▸ | ADRB1 | P08588 | 1/20 | 0.40 |
| ▸ | ADRB3 | P13945 | 1/20 | 0.40 |
| ▸ | CYP2D6 | P10635 | 2/20 | 0.39 |
| ▸ | CYP2C19 | P33261 | 2/20 | 0.39 |
| ▸ | ATM | Q13315 | 1/20 | 0.39 |
| ▸ | OPRM1 | P35372 | 1/20 | 0.39 |
| ▸ | OPRD1 | P41143 | 1/20 | 0.39 |
| ▸ | OPRK1 | P41145 | 1/20 | 0.39 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.39 |
| ▸ | CYP2C9 | P11712 | 1/20 | 0.39 |
| ▸ | HTT | P42858 | 1/20 | 0.39 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6679118 | 0.85 | SENP1 (0.49) | MAPTRAB9AALDH1A1SMN1; SMN2HTT | |
| SCHEMBL6685806 | 0.82 | ACHE (0.43) | KMT2AMEN1ALDH1A1SMN1; SMN2LMNA | |
| SCHEMBL6678217 | 0.81 | KDM1A (0.40) | KMT2AMEN1NPC1MAPTRAB9A | |
| SCHEMBL6685803 | 0.80 | ALDH1A1 (0.41) | KMT2AMEN1NPC1MAPTRAB9A | |
| SCHEMBL6688950 | 0.78 | GLS (0.42) | KMT2AMEN1NPC1MAPTRAB9A | |
| SCHEMBL6676115 | 0.76 | NAMPT (0.53) | KMT2AMAPTLMNACA1CA2 | |
| SCHEMBL6675938 | 0.74 | CYP3A4 (0.47) | ALDH1A1CYP2C19CYP3A4CYP2C9LMNA | |
| SCHEMBL6676462 | 0.74 | MAPT (0.46) | KMT2AMEN1NPC1MAPTRAB9A | |
| SCHEMBL6685807 | 0.74 | CYP2D6 (0.42) | KMT2AMEN1ALDH1A1SMN1; SMN2TP53 | |
| SCHEMBL6679078 | 0.73 | NR1H2 (0.50) | NPC1MAPTRAB9ASMN1; SMN2LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |