Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.36 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.36 |
| ▸ | BTK | Q06187 | 1/20 | 0.34 |
| ▸ | METAP2 | P50579 | 3/20 | 0.33 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.33 |
| ▸ | EPHX2 | P34913 | 2/20 | 0.33 |
| ▸ | USP30 | Q70CQ3 | 1/20 | 0.33 |
| ▸ | METAP1 | P53582 | 1/20 | 0.33 |
| ▸ | MEN1 | O00255 | 1/20 | 0.33 |
| ▸ | POLB | P06746 | 1/20 | 0.33 |
| ▸ | OPRL1 | P41146 | 1/20 | 0.33 |
| ▸ | MAPT | P10636 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 3/20 | 0.32 |
| ▸ | RAB9A | P51151 | 2/20 | 0.32 |
| ▸ | EPHX1 | P07099 | 1/20 | 0.32 |
| ▸ | PARP10 | Q53GL7 | 1/20 | 0.32 |
| ▸ | CTSD | P07339 | 1/20 | 0.32 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | GAA | P10253 | 1/20 | 0.32 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685915 | 0.91 | RAB9A (0.35) | ALDH1A1KMT2AMEN1POLBOPRL1 | |
| SCHEMBL6690873 | 0.85 | RAB9A (0.40) | ALDH1A1POLBOPRL1NPC1RAB9A | |
| SCHEMBL6685681 | 0.84 | EPHX2 (0.48) | ALDH1A1L3MBTL1METAP2KMT2AEPHX2 | |
| SCHEMBL6686989 | 0.83 | BTK (0.35) | ALDH1A1L3MBTL1BTKOPRL1NPC1 | |
| SCHEMBL6685728 | 0.82 | RAB9A (0.39) | ALDH1A1KMT2AMEN1OPRL1MAPT | |
| SCHEMBL6687208 | 0.81 | TRPA1 (0.35) | ALDH1A1L3MBTL1KMT2AMEN1OPRL1 | |
| SCHEMBL6693494 | 0.81 | SLC6A9 (0.37) | NPC1RAB9AEPHX1PARP10SLC6A9 | |
| SCHEMBL6685923 | 0.81 | RAB9A (0.38) | POLBNPC1RAB9AEPHX1 | |
| SCHEMBL6693491 | 0.79 | NPC1 (0.42) | ALDH1A1L3MBTL1KMT2AEPHX2MEN1 | |
| SCHEMBL6688322 | 0.78 | TP53 (0.43) | ALDH1A1KMT2AMEN1NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |