Predicted protein targets (top 16)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | BTK | Q06187 | 1/20 | 0.35 |
| ▸ | OPRL1 | P41146 | 4/20 | 0.34 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | NPC1 | O15118 | 5/20 | 0.33 |
| ▸ | RAB9A | P51151 | 5/20 | 0.33 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.33 |
| ▸ | TSHR | P16473 | 1/20 | 0.32 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.32 |
| ▸ | CFD | P00746 | 2/20 | 0.32 |
| ▸ | CD38 | P28907 | 1/20 | 0.32 |
| ▸ | P2RX7 | Q99572 | 1/20 | 0.31 |
| ▸ | EBP | Q15125 | 1/20 | 0.31 |
| ▸ | SIGMAR1 | Q99720 | 1/20 | 0.31 |
| ▸ | CSF1R | P07333 | 1/20 | 0.31 |
| ▸ | EGFR | P00533 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685728 | 0.90 | RAB9A (0.39) | OPRL1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6690873 | 0.84 | RAB9A (0.40) | OPRL1ALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6686689 | 0.83 | ALDH1A1 (0.36) | BTKOPRL1ALDH1A1NPC1RAB9A | |
| SCHEMBL6687208 | 0.82 | TRPA1 (0.35) | OPRL1ALDH1A1L3MBTL1CD38 | |
| SCHEMBL6685681 | 0.82 | EPHX2 (0.48) | ALDH1A1NPC1RAB9AL3MBTL1TSHR | |
| SCHEMBL6688322 | 0.81 | TP53 (0.43) | KDM4EALDH1A1NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6693491 | 0.81 | NPC1 (0.42) | KDM4EALDH1A1NPC1RAB9AL3MBTL1 | |
| SCHEMBL6685923 | 0.80 | RAB9A (0.38) | NPC1RAB9ASMN1; SMN2 | |
| SCHEMBL6685915 | 0.80 | RAB9A (0.35) | OPRL1ALDH1A1NPC1RAB9ATSHR | |
| SCHEMBL6693494 | 0.78 | SLC6A9 (0.37) | NPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004084843-A2 | INHIBITORS OF CATHEPSIN S | IRM LLC (BM) | 2004-10-07 | — | — | WO | disclosed |