SCHEMBL6686752

SCHEMBL6686752

CC1[C@H](C(N)=O)OC(=O)N1c1ccc2c(c1)CCN(C=O)CC2

nearest known ligand 0.37

Predicted protein targets (top 2)

geneUniProtsupporting neighboursconfidence
HTR6 P50406 4/20 0.32
PDE4D Q08499 1/20 0.32

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL6686228 0.89 TMEM97 (0.33) PDE4D
SCHEMBL3035135 0.76 MAOA (0.47) HTR6
SCHEMBL5792891 0.75 CYP11B2 (0.40)
SCHEMBL3039308 0.69 HTR6 (0.42) HTR6
SCHEMBL6040433 0.67 MAOA (0.56)
SCHEMBL6691654 0.67 MAOA (0.35)
SCHEMBL3039459 0.65 MAOA (0.45) HTR6
SCHEMBL6087072 0.64 MAOA (0.39)
Hydrochloric Acid SCHEMBL7086927 0.64 RAB9A (0.47) PDE4D
SCHEMBL6672496 0.64 TIPARP (0.38)

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
EP-1478629-A1 N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATIVES AND THEIR USE AS ANTIBACTERIALS PHARMACIA & UPJOHN COMPANY (US) 2004-11-24 EP disclosed
WO-2003072553-A1 N-ARYL-2-OXAZOLIDINONE-5-CARBOXAMIDES AND THEIR DERIVATES AND THEIR USE AS ANTIBACTERIALS PHARMACIA & UPJOHN COMPANY (US) 2003-09-04 WO disclosed