SCHEMBL668680

SCHEMBL668680

[c]1ccccc1-c1c(-c2ccccc2)ccc2ccccc12

nearest known ligand 0.39

Predicted protein targets (top 20)

geneUniProtsupporting neighboursconfidence
DNMT1 P26358 1/20 0.39
WDR5 P61964 1/20 0.36
KDM4E B2RXH2 5/20 0.36
MEN1 O00255 4/20 0.36
KMT2A Q03164 4/20 0.36
GPR84 Q9NQS5 2/20 0.36
ALDH1A1 P00352 5/20 0.35
TSHR P16473 2/20 0.35
HSD17B10 Q99714 2/20 0.35
CYP2A6 P11509 1/20 0.35
TDP1 Q9NUW8 1/20 0.35
MAPT P10636 5/20 0.35
HPGD P15428 4/20 0.35
MPI P34949 1/20 0.35
CYP1A2 P05177 6/20 0.35
CYP1A1 P04798 5/20 0.35
CYP1B1 Q16678 4/20 0.35
NQO2 P16083 1/20 0.33
HPRT1 P00492 1/20 0.33
TNF P01375 1/20 0.33

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL8859334 0.87 DNMT1 (0.39) DNMT1WDR5KDM4EMEN1KMT2A
SCHEMBL8859512 0.86 ESR1 (0.34) MEN1KMT2AGPR84MAPTLMNA
SCHEMBL22061739 0.86 MEN1 (0.36) KDM4EMEN1KMT2AGPR84ALDH1A1
SCHEMBL8859382 0.84 ESR1 (0.46) KDM4EMEN1KMT2AGPR84MAPT
SCHEMBL8859504 0.83 RAB9A (0.35) GPR84ALDH1A1HSD17B10CYP2A6HPGD
SCHEMBL669468 0.83 DNMT1 (0.46) DNMT1WDR5KDM4EMEN1KMT2A
SCHEMBL8859389 0.83 CYP2A6 (0.40) KDM4EMEN1KMT2AALDH1A1HSD17B10
SCHEMBL8859344 0.83 MAPK1 (0.39) KDM4EMEN1KMT2AALDH1A1HSD17B10
SCHEMBL8859374 0.82 KMT2A (0.37) KDM4EMEN1KMT2AGPR84ALDH1A1
SCHEMBL8859427 0.82 PSMB5 (0.39) KDM4EMEN1KMT2AGPR84ALDH1A1

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 47 patents — showing the first 20. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
US-20240172559-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM,LTD. (KR) 2024-05-23 US claimed
WO-2021162227-A1 NOVEL COMPOUND AND ORGANIC LIGHT-EMITTING DEVICE USING SAME 주식회사 엘지화학 2021-08-19 WO claimed
US-20240172559-A1 ORGANIC LIGHT EMITTING DEVICE LG CHEM,LTD. (KR) 2024-05-23 US disclosed
CN-116671280-A Organic light emitting device 株式会社LG化学 2023-08-29 CN disclosed
WO-2023003436-A1 ORGANIC LIGHT-EMITTING DEVICE 주식회사 엘지화학 2023-01-26 WO disclosed
CN-109790131-B Heterocyclic compound and organic light-emitting device comprising same 株式会社LG化学 2022-09-06 CN disclosed
CN-112812024-B Organic compound, application and organic electroluminescent device using organic compound 陕西莱特迈思光电材料有限公司 2022-03-29 CN disclosed
US-11251377-B2 Organic light emitting device LG CHEM, LTD. (KR) 2022-02-15 US disclosed
US-11189800-B2 Heterocyclic compound and organic light emitting device comprising the same LG CHEM, LTD. (KR) 2021-11-30 US disclosed
WO-2021136055-A1 NITROGEN-CONTAINING ORGANIC COMPOUND, USE THEREOF, AND ORGANIC ELECTROLUMINESCENT DEVICE USING SAME 陕西莱特光电材料股份有限公司 2021-07-08 WO disclosed
CN-112812024-A Organic compound, application and organic electroluminescent device using organic compound 陕西莱特迈思光电材料有限公司 2021-05-18 CN disclosed
EP-2159217-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2010-03-03 EP disclosed
EP-2124270-A1 ORGANIC EL DEVICE Idemitsu Kosan Co., Ltd. (JP) 2009-11-25 EP disclosed
EP-2085371-A1 FLUORANTHENE COMPOUND, ORGANIC ELECTROLUMINESCENT DEVICE USING THE FLUORANTHENE COMPOUND, AND ORGANIC ELECTROLUMINESCENT MATERIAL-CONTAINING SOLUTION Idemitsu Kosan Co., Ltd. (JP) 2009-08-05 EP disclosed
US-20090167156-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2009-07-02 US disclosed
US-20090015144-A1 FLUORANTHENE COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME, AND SOLUTION CONTAINING ORGANIC ELECTROLUMINESCENCE MATERIAL IDEMITSU KOSAN CO., LTD. (JP) 2009-01-15 US disclosed
EP-2008992-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENT DEVICE USING THE SAME Idemitsu Kosan Co., Ltd. (JP) 2008-12-31 EP disclosed
EP-1990844-A1 ORGANIC ELECTROLUMINESCENT DEVICE Idemitsu Kosan Co., Ltd. (JP) 2008-11-12 EP disclosed
US-20080004445-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME IDEMITSU KOSAN CO., LTD. (JP) 2008-01-03 US disclosed
US-20070243411-A1 ORGANIC ELECTROLUMINESCENCE DEVICE IDEMITSU KOSAN CO., LTD. (JP) 2007-10-18 US disclosed

Patent text — is the patent's own abstract consistent with the prediction?

For each of this compound's patents that has machine-readable text (4 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.

PatentTitleText reads most aboutPredicted target · text-rank
US-20080004445-A1 AROMATIC AMINE DERIVATIVE AND ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME TYR, MAOA, PRDM9 DNMT1 113/4885WDR5 2963/4885KDM4E 126/4885
US-20240172559-A1 ORGANIC LIGHT EMITTING DEVICE CRY1, CRY2, CYP1A1 DNMT1 1524/4885WDR5 2653/4885KDM4E 3863/4885
US-11189800-B2 Heterocyclic compound and organic light emitting device comprising the same CRY1, CYBA, CYP1B1 DNMT1 921/4885WDR5 3447/4885KDM4E 2736/4885
US-20090015144-A1 FLUORANTHENE COMPOUND, ORGANIC ELECTROLUMINESCENCE DEVICE USING THE SAME, AND SOLUTION CONTAINING ORGANIC ELECTROLUMINESCENCE MATERIAL LEF1, ESD, AFF2 DNMT1 528/4885WDR5 4281/4885KDM4E 1881/4885

“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.