Predicted protein targets (top 13)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | NQO2 | P16083 | 1/20 | 0.38 |
| ▸ | MTNR1A | P48039 | 5/20 | 0.38 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.38 |
| ▸ | NPC1 | O15118 | 2/20 | 0.38 |
| ▸ | RAB9A | P51151 | 2/20 | 0.38 |
| ▸ | BRD4 | O60885 | 1/20 | 0.38 |
| ▸ | MTNR1B | P49286 | 2/20 | 0.37 |
| ▸ | MAPT | P10636 | 1/20 | 0.36 |
| ▸ | CA12 | O43570 | 2/20 | 0.36 |
| ▸ | CA1 | P00915 | 2/20 | 0.36 |
| ▸ | CA2 | P00918 | 2/20 | 0.36 |
| ▸ | CA9 | Q16790 | 2/20 | 0.36 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.35 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6682001 | 0.83 | CA1 (0.41) | MAPTCA12CA1CA2CA9 | |
| SCHEMBL8771555 | 0.83 | IDO1 (0.39) | NQO2KDM4ENPC1RAB9AMAPT | |
| SCHEMBL6676265 | 0.81 | CA2 (0.40) | NQO2KDM4EMAPTCA1CA2 | |
| SCHEMBL8771747 | 0.80 | CA2 (0.39) | NQO2MAPTCA1CA2 | |
| SCHEMBL6681075 | 0.80 | NQO2 (0.39) | NQO2KDM4ENPC1RAB9AMAPT | |
| SCHEMBL6675284 | 0.80 | ESRRG (0.42) | NQO2KDM4EMAPTCA1CA2 | |
| SCHEMBL6687614 | 0.78 | IDO1 (0.41) | NQO2KDM4ENPC1RAB9AMAPT | |
| SCHEMBL6676118 | 0.77 | CA2 (0.47) | KDM4ENPC1RAB9AMAPTCA1 | |
| SCHEMBL6675304 | 0.75 | MTNR1A (0.41) | NQO2MTNR1AKDM4ENPC1RAB9A | |
| SCHEMBL6675910 | 0.75 | MTNR1A (0.48) | NQO2MTNR1AKDM4ENPC1RAB9A |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 2 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0798292-B1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | CHUGAI SEIYAKUKABUSHIKI KAISHA (JP) | 2004-11-03 | — | — | EP | disclosed |
| EP-0798292-A1 | ANILINE DERIVATIVES HAVING NITROGEN MONOXIDE SYNTHASE INHIBITORY ACTIVITY | Chugai Seiyaku Kabushiki Kaisha (JP) | 1997-10-01 | — | — | EP | disclosed |