Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MMP9 | P14780 | 4/20 | 0.52 |
| ▸ | MMP1 | P03956 | 4/20 | 0.52 |
| ▸ | MMP13 | P45452 | 4/20 | 0.52 |
| ▸ | MMP2 | P08253 | 3/20 | 0.52 |
| ▸ | SOS1 | Q07889 | 1/20 | 0.50 |
| ▸ | F2 | P00734 | 1/20 | 0.49 |
| ▸ | PRSS1 | P07477 | 1/20 | 0.49 |
| ▸ | PRSS2 | P07478 | 1/20 | 0.49 |
| ▸ | PRSS3 | P35030 | 1/20 | 0.49 |
| ▸ | ST14 | Q9Y5Y6 | 1/20 | 0.49 |
| ▸ | MMP3 | P08254 | 2/20 | 0.49 |
| ▸ | MMP7 | P09237 | 2/20 | 0.49 |
| ▸ | ADAMTS4 | O75173 | 2/20 | 0.48 |
| ▸ | SLC1A3 | P43003 | 1/20 | 0.48 |
| ▸ | SLC1A2 | P43004 | 1/20 | 0.48 |
| ▸ | SLC1A1 | P43005 | 1/20 | 0.48 |
| ▸ | FFAR1 | O14842 | 1/20 | 0.48 |
| ▸ | FFAR4 | Q5NUL3 | 1/20 | 0.48 |
| ▸ | SCN9A | Q15858 | 7/20 | 0.47 |
| ▸ | BCL2L1 | Q07817 | 1/20 | 0.47 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6687951 | 1.00 | MMP9 (0.52) | MMP9MMP1MMP13MMP2SOS1 | |
| SCHEMBL1798547 | 0.87 | MMP9 (0.67) | MMP9MMP1MMP13MMP2SOS1 | |
| SCHEMBL1798546 | 0.87 | MMP9 (0.67) | MMP9MMP1MMP13MMP2SOS1 | |
| SCHEMBL1796948 | 0.85 | MMP1 (0.60) | MMP9MMP1MMP13MMP2MMP3 | |
| SCHEMBL1796951 | 0.85 | MMP1 (0.60) | MMP9MMP1MMP13MMP2MMP3 | |
| SCHEMBL7468779 | 0.77 | ADAMTS4 (0.69) | MMP9MMP1MMP13MMP2MMP3 | |
| SCHEMBL6806364 | 0.77 | ADAMTS4 (0.69) | MMP9MMP1MMP13MMP2MMP3 | |
| SCHEMBL7468791 | 0.77 | ADAMTS4 (0.69) | MMP9MMP1MMP13MMP2MMP3 | |
| SCHEMBL1903552 | 0.77 | SLC1A3 (0.56) | MMP9MMP1MMP13MMP2F2 | |
| SCHEMBL27560159 | 0.77 | CA12 (0.54) | MMP9MMP1MMP13MMP2MMP3 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004087125-A1 | AMINO ACID DERIVATIVES AS INHIBITORS OF MAMMALIAN SODIUM CHANNELS | IONIX PHARMACEUTICALS LIMITED (GB) | 2004-10-14 | — | — | WO | disclosed |