Predicted protein targets (top 11)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.64 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.64 |
| ▸ | KEAP1 | Q14145 | 2/20 | 0.59 |
| ▸ | HTT | P42858 | 2/20 | 0.59 |
| ▸ | POLB | P06746 | 3/20 | 0.57 |
| ▸ | NFE2L2 | Q16236 | 1/20 | 0.57 |
| ▸ | MAPT | P10636 | 3/20 | 0.56 |
| ▸ | MEN1 | O00255 | 2/20 | 0.56 |
| ▸ | KMT2A | Q03164 | 2/20 | 0.56 |
| ▸ | LMNA | P02545 | 1/20 | 0.54 |
| ▸ | ADORA2A | P29274 | 1/20 | 0.50 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6685365 | 0.85 | ALDH1A1 (0.48) | ALDH1A1L3MBTL1KEAP1HTTPOLB | |
| SCHEMBL11574848 | 0.83 | ALDH1A1 (0.64) | ALDH1A1L3MBTL1KEAP1HTTPOLB | |
| SCHEMBL7164415 | 0.81 | ALDH1A1 (0.89) | ALDH1A1L3MBTL1KEAP1HTTPOLB | |
| SCHEMBL13065512 | 0.81 | MAOA (0.48) | ALDH1A1L3MBTL1KEAP1HTTPOLB | |
| SCHEMBL7121384 | 0.80 | KEAP1 (0.86) | ALDH1A1L3MBTL1KEAP1POLBNFE2L2 | |
| SCHEMBL8675450 | 0.80 | ALDH1A1 (0.70) | ALDH1A1L3MBTL1KEAP1HTTPOLB | |
| SCHEMBL27360880 | 0.80 | ALDH1A1 (0.75) | ALDH1A1L3MBTL1KEAP1POLBNFE2L2 | |
| SCHEMBL27637350 | 0.79 | KEAP1 (0.83) | ALDH1A1L3MBTL1KEAP1POLBNFE2L2 | |
| SCHEMBL11180219 | 0.79 | ALDH1A1 (0.58) | ALDH1A1L3MBTL1KEAP1HTTPOLB | |
| Anthraquinone SCHEMBL8941397 | 0.78 | ALDH1A1 (1.00) | ALDH1A1L3MBTL1KEAP1POLBNFE2L2 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6824998-B2 | FOR DETERMINATION IN MAMMALS VIA 1-ANTHRAQUINONYLHYDRAZIDE WITH P-ANIALDEHYDE; DRUG SCREENING; PACKAGING; KITS | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2004-11-30 | — | — | US | disclosed |
| WO-2004083861-A1 | COMPOUNDS AND METHODS FOR DETECTING TRIPEPTIDYL PROTEASE I | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2004-09-30 | — | — | WO | disclosed |
| US-20040185520-A1 | Compounds and methods for detecting tripeptidyl protease I | AKRION, INC. | 2004-09-23 | — | — | US | disclosed |
| US-4927865-A | CURABLE EPOXY RESINS | CIBA-GEIGY CORPORATION (US) | 1990-05-22 | — | — | US | disclosed |
| US-4855084-A | PHOTOSENSITIVE COMPOSITIONS | CIBA-GEIGY CORPORATION (US) | 1989-08-08 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040185520-A1 | Compounds and methods for detecting tripeptidyl protease I | TPP1, DNPEP, TPP2 | ALDH1A1 183/4885L3MBTL1 432/4885KEAP1 1157/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.