Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | PDK2 | Q15119 | 1/20 | 0.35 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.35 |
| ▸ | MGAT2 | Q10469 | 2/20 | 0.34 |
| ▸ | MAPT | P10636 | 2/20 | 0.32 |
| ▸ | FLT3 | P36888 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
| ▸ | BACE1 | P56817 | 2/20 | 0.32 |
| ▸ | KCNH2 | Q12809 | 1/20 | 0.32 |
| ▸ | MEN1 | O00255 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | RAB9A | P51151 | 1/20 | 0.32 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.32 |
| ▸ | DYRK1A | Q13627 | 1/20 | 0.32 |
| ▸ | EDNRA | P25101 | 1/20 | 0.31 |
| ▸ | CYP11B1 | P15538 | 1/20 | 0.31 |
| ▸ | CYP11B2 | P19099 | 1/20 | 0.31 |
| ▸ | ALKBH3 | Q96Q83 | 1/20 | 0.31 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.31 |
| ▸ | ACHE | P22303 | 1/20 | 0.31 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689248 | 0.81 | HDAC9 (0.33) | MEN1KMT2ACHRM5 | |
| SCHEMBL9546931 | 0.74 | MAOA (0.36) | MEN1RAB9AKMT2A | |
| SCHEMBL7455420 | 0.73 | ACHE (0.37) | CHRM5ACHE | |
| SCHEMBL6689370 | 0.73 | MAPT (0.35) | MAPTMEN1NPC1KMT2AKDM4E | |
| SCHEMBL6689781 | 0.72 | OPRM1 (0.32) | — | |
| SCHEMBL9113335 | 0.71 | MAPT (0.36) | MAPTCYP1A2NPC1RAB9AKMT2A | |
| SCHEMBL5072171 | 0.68 | — | — | |
| SCHEMBL7729865 | 0.63 | SLC6A2 (0.33) | — | |
| SCHEMBL7972739 | 0.62 | MAPT (0.43) | MAPTMEN1RAB9AKMT2AKDM4E | |
| SCHEMBL12871359 | 0.61 | ABL1 (0.71) | CYP3A4FLT3CYP1A2CYP2C19MEN1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 5 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-1042311-A1 | PHOTOCHROMIC 6-ARYL SUBSTITUTED 3H-NAPHTHO 2,1-b]PYRANS | TRANSITIONS OPTICAL, INC. (US) | 2000-10-11 | — | — | EP | claimed |
| WO-1999031082-A1 | PHOTOCHROMIC 6-ARYL SUBSTITUTED 3H-NAPHTHO[2,1-b]PYRANS | TRANSITIONS OPTICAL, INC. (US) | 1999-06-24 | — | — | WO | claimed |
| EP-3331581-A1 | MECHANOPHORIC MEDICAL PRODUCT | Aesculap AG (DE) | 2018-06-13 | — | — | EP | disclosed |
| EP-1042311-A1 | PHOTOCHROMIC 6-ARYL SUBSTITUTED 3H-NAPHTHO 2,1-b]PYRANS | TRANSITIONS OPTICAL, INC. (US) | 2000-10-11 | — | — | EP | disclosed |
| WO-1999031082-A1 | PHOTOCHROMIC 6-ARYL SUBSTITUTED 3H-NAPHTHO[2,1-b]PYRANS | TRANSITIONS OPTICAL, INC. (US) | 1999-06-24 | — | — | WO | disclosed |