Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAPT | P10636 | 5/20 | 0.35 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.35 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.35 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | ELANE | P08246 | 1/20 | 0.34 |
| ▸ | LMNA | P02545 | 2/20 | 0.34 |
| ▸ | MEN1 | O00255 | 1/20 | 0.34 |
| ▸ | USP2 | O75604 | 1/20 | 0.34 |
| ▸ | HTT | P42858 | 1/20 | 0.34 |
| ▸ | KMT2A | Q03164 | 1/20 | 0.34 |
| ▸ | MAPK14 | Q16539 | 1/20 | 0.33 |
| ▸ | CA2 | P00918 | 2/20 | 0.33 |
| ▸ | CA5A | P35218 | 2/20 | 0.33 |
| ▸ | GAA | P10253 | 2/20 | 0.33 |
| ▸ | HSP90AA1 | P07900 | 1/20 | 0.33 |
| ▸ | KDM4E | B2RXH2 | 2/20 | 0.32 |
| ▸ | PTPN1 | P18031 | 1/20 | 0.32 |
| ▸ | RXFP1 | Q9HBX9 | 1/20 | 0.32 |
| ▸ | NPC1 | O15118 | 1/20 | 0.32 |
| ▸ | POLB | P06746 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL8310687 | 0.89 | MAPT (0.41) | MAPTALDH1A1SMN1; SMN2MAPK1ELANE | |
| SCHEMBL8310120 | 0.79 | ELANE (0.43) | MAPTALDH1A1SMN1; SMN2MAPK1ELANE | |
| SCHEMBL6689781 | 0.76 | OPRM1 (0.32) | — | |
| SCHEMBL8313929 | 0.71 | MAPT (0.43) | MAPTALDH1A1SMN1; SMN2MEN1KMT2A | |
| SCHEMBL6689248 | 0.70 | HDAC9 (0.33) | ALDH1A1MEN1KMT2A | |
| SCHEMBL5072171 | 0.67 | — | — | |
| SCHEMBL9546931 | 0.67 | MAOA (0.36) | SMN1; SMN2LMNAMEN1KMT2A | |
| SCHEMBL29359986 | 0.64 | CA2 (0.46) | MAPTALDH1A1SMN1; SMN2MAPK1ELANE | |
| SCHEMBL926822 | 0.64 | CA2 (0.46) | MAPTALDH1A1SMN1; SMN2MAPK1ELANE | |
| SCHEMBL8853861 | 0.64 | PTGS2 (0.41) | MAPTALDH1A1SMN1; SMN2MAPK1LMNA |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004085568-A2 | PHOTOCHROMIC ARTICLES WITH REDUCED TEMPERATURE DEPENDENCY AND METHODS FOR PREPARATION | TRANSITIONS OPTICAL, INC. (US) | 2004-10-07 | — | — | WO | disclosed |