Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | HPGD | P15428 | 5/20 | 0.40 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.40 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.40 |
| ▸ | HSD17B10 | Q99714 | 2/20 | 0.40 |
| ▸ | L3MBTL1 | Q9Y468 | 4/20 | 0.36 |
| ▸ | TSHR | P16473 | 2/20 | 0.35 |
| ▸ | NPC1 | O15118 | 3/20 | 0.34 |
| ▸ | RAB9A | P51151 | 3/20 | 0.34 |
| ▸ | ALOX15 | P16050 | 2/20 | 0.34 |
| ▸ | TP53 | P04637 | 1/20 | 0.34 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.34 |
| ▸ | SMN1; SMN2 | Q16637 | 1/20 | 0.34 |
| ▸ | GAA | P10253 | 5/20 | 0.33 |
| ▸ | MAPT | P10636 | 2/20 | 0.33 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.33 |
| ▸ | LMNA | P02545 | 1/20 | 0.32 |
| ▸ | CYP1A2 | P05177 | 1/20 | 0.32 |
| ▸ | CYP3A4 | P08684 | 1/20 | 0.32 |
| ▸ | CASP1 | P29466 | 1/20 | 0.32 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.32 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6689781 | 0.74 | OPRM1 (0.32) | — | |
| SCHEMBL6536806 | 0.73 | — | — | |
| SCHEMBL6689248 | 0.71 | HDAC9 (0.33) | ALDH1A1MEN1KMT2A | |
| SCHEMBL6036708 | 0.69 | ALDH1A1 (0.62) | HPGDALDH1A1KDM4EHSD17B10L3MBTL1 | |
| SCHEMBL5072171 | 0.68 | — | — | |
| SCHEMBL6536500 | 0.68 | ATM (0.34) | ALDH1A1L3MBTL1LMNAPOLB | |
| SCHEMBL7972739 | 0.67 | MAPT (0.43) | ALDH1A1KDM4EL3MBTL1RAB9ATP53 | |
| SCHEMBL9546931 | 0.65 | MAOA (0.36) | L3MBTL1RAB9ASMN1; SMN2LMNAMEN1 | |
| SCHEMBL6687407 | 0.64 | TMEM97 (0.44) | HPGDALDH1A1KDM4ETSHRNPC1 | |
| SCHEMBL9424119 | 0.63 | LMNA (0.62) | HPGDALDH1A1KDM4EHSD17B10L3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-7898176-B2 | Fluidic thermal management article and method | GENERAL ELECTRIC COMPANY (US) | 2011-03-01 | — | — | US | disclosed |
| US-20090087640-A1 | FLUIDIC THERMAL MANAGEMENT ARTICLE AND METHOD | GENERAL ELECTRIC COMPANY (US) | 2009-04-02 | — | — | US | disclosed |
| US-20080252202-A1 | LIGHT-EMITTING DEVICE AND ARTICLE | GENERAL ELECTRIC COMPANY (US) | 2008-10-16 | — | — | US | disclosed |