SCHEMBL6689816

SCHEMBL6689816

N#CCNS(=O)(=O)c1cccc(Cl)c1

nearest known ligand 0.57

Predicted protein targets (top 14)

geneUniProtsupporting neighboursconfidence
PGR P06401 5/20 0.51
KAT6A Q92794 1/20 0.49
FBP1 P09467 5/20 0.49
PKM P14618 2/20 0.49
HSD11B1 P28845 1/20 0.48
LMNA P02545 1/20 0.48
MAPT P10636 1/20 0.48
TDP1 Q9NUW8 1/20 0.48
CTSL P07711 1/20 0.47
CTSS P25774 1/20 0.47
ALDH1A1 P00352 1/20 0.47
GAA P10253 1/20 0.47
KMT2A Q03164 1/20 0.47
L3MBTL1 Q9Y468 1/20 0.47

Click a target to see other patent compounds predicted against it — the reverse direction, in place.

Similar compounds — the chemically nearest patent molecules

Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.

Compoundsimilaritytop predictedshared targets
SCHEMBL3368190 0.84 PGR (0.51) PGRKAT6AFBP1PKMHSD11B1
SCHEMBL8377902 0.81 PGR (0.56) PGRKAT6AFBP1PKMHSD11B1
SCHEMBL9870931 0.81 FBP1 (0.52) PGRFBP1PKMLMNAALDH1A1
SCHEMBL16333682 0.81 ATM (0.56) PGRKAT6ATDP1CTSLCTSS
SCHEMBL10389233 0.79 ALDH1A1 (0.55) PKMLMNACTSLALDH1A1L3MBTL1
SCHEMBL28584618 0.78 PGR (0.56) PGRKAT6AFBP1PKMHSD11B1
SCHEMBL7863564 0.77 PGR (0.60) PGRKAT6AFBP1PKMLMNA
SCHEMBL6850559 0.76 KAT6A (0.61) PGRKAT6AFBP1HSD11B1
SCHEMBL31014170 0.76 LMNA (0.56) PGRFBP1PKMLMNATDP1
SCHEMBL2371349 0.75 LMNA (0.61) PGRFBP1PKMLMNAMAPT

Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.

Patent provenance — the patents this molecule appears in, and who filed them

Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.

PatentTitleAssigneePublishedPriorityFilingCountryStatus
WO-2004085400-A1 SUBSTITUTED PYRI(MI)DIN(THIO)CARBOXAMIDES USED AS PESTICIDES BAYER CROPSCIENCE AG (DE) 2004-10-07 WO disclosed