Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | MAOA | P21397 | 1/20 | 0.44 |
| ▸ | PTPRC | P08575 | 2/20 | 0.41 |
| ▸ | MALT1 | Q9UDY8 | 1/20 | 0.41 |
| ▸ | MEN1 | O00255 | 3/20 | 0.40 |
| ▸ | KMT2A | Q03164 | 3/20 | 0.40 |
| ▸ | MMP14 | P50281 | 1/20 | 0.40 |
| ▸ | TERT | O14746 | 3/20 | 0.39 |
| ▸ | CYP1A2 | P05177 | 2/20 | 0.39 |
| ▸ | TSHR | P16473 | 1/20 | 0.39 |
| ▸ | MAPT | P10636 | 4/20 | 0.39 |
| ▸ | MITF | O75030 | 1/20 | 0.39 |
| ▸ | ALDH1A1 | P00352 | 3/20 | 0.39 |
| ▸ | MAPK1 | P28482 | 1/20 | 0.39 |
| ▸ | NPSR1 | Q6W5P4 | 1/20 | 0.39 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.39 |
| ▸ | TDP2 | O95551 | 1/20 | 0.38 |
| ▸ | POLB | P06746 | 1/20 | 0.38 |
| ▸ | GAA | P10253 | 1/20 | 0.38 |
| ▸ | DNMT1 | P26358 | 1/20 | 0.38 |
| ▸ | RAD52 | P43351 | 1/20 | 0.38 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL18623980 | 0.78 | MEN1 (0.61) | MAOAMALT1MEN1KMT2AMMP14 | |
| SCHEMBL18623984 | 0.72 | MALT1 (0.44) | MALT1MEN1KMT2ATERTPOLB | |
| SCHEMBL22336061 | 0.70 | PTPRC (0.63) | MAOAPTPRCMEN1KMT2ACYP1A2 | |
| SCHEMBL29465938 | 0.70 | PTPRC (0.63) | MAOAPTPRCMEN1KMT2ACYP1A2 | |
| SCHEMBL2880191 | 0.69 | LMNA (0.54) | MEN1KMT2AALDH1A1POLBGAA | |
| SCHEMBL3822356 | 0.68 | CA12 (0.42) | MEN1KMT2APOLBGAAELANE | |
| SCHEMBL18295333 | 0.67 | LMNA (0.45) | TSHRMAPTALDH1A1POLBGAA | |
| SCHEMBL22007092 | 0.67 | PTPRC (0.63) | MAOAPTPRCMEN1KMT2ACYP1A2 | |
| SCHEMBL3788603 | 0.67 | HSP90AA1 (0.46) | MAOAMALT1MEN1KMT2AMMP14 | |
| SCHEMBL11742788 | 0.67 | MAOA (0.73) | MAOAPTPRCMEN1KMT2ATERT |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| US-6824998-B2 | FOR DETERMINATION IN MAMMALS VIA 1-ANTHRAQUINONYLHYDRAZIDE WITH P-ANIALDEHYDE; DRUG SCREENING; PACKAGING; KITS | UNIVERSITY OF IOWA RESEARCH FOUNDATION | 2004-11-30 | — | — | US | disclosed |
| WO-2004083861-A1 | COMPOUNDS AND METHODS FOR DETECTING TRIPEPTIDYL PROTEASE I | UNIVERSITY OF IOWA RESEARCH FOUNDATION (US) | 2004-09-30 | — | — | WO | disclosed |
| US-20040185520-A1 | Compounds and methods for detecting tripeptidyl protease I | AKRION, INC. | 2004-09-23 | — | — | US | disclosed |
Patent text — is the patent's own abstract consistent with the prediction?
For each of this compound's patents that has machine-readable text (1 of them — usually the abstract, not the full specification), we ask MedCPT which protein the text reads most about, and where the chemistry-predicted target lands among 4885 human targets. A high rank means the patent's own wording is consistent with the prediction — a weak, independent signal, not proof of activity.
| Patent | Title | Text reads most about | Predicted target · text-rank |
|---|---|---|---|
| US-20040185520-A1 | Compounds and methods for detecting tripeptidyl protease I | TPP1, DNPEP, TPP2 | MAOA 2137/4885PTPRC 2678/4885MALT1 3432/4885 |
“Text reads most about” is the patent abstract's nearest protein in MedCPT space (background-debiased). Only ~1.4% of patents have machine-readable text, so most compounds won't have this panel.