Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 5/20 | 0.49 |
| ▸ | MEN1 | O00255 | 3/20 | 0.49 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.48 |
| ▸ | HTT | P42858 | 1/20 | 0.47 |
| ▸ | DRD3 | P35462 | 1/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.47 |
| ▸ | HPGD | P15428 | 2/20 | 0.46 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.46 |
| ▸ | POLB | P06746 | 2/20 | 0.45 |
| ▸ | ALDH1A1 | P00352 | 2/20 | 0.45 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.45 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.45 |
| ▸ | DRD2 | P14416 | 3/20 | 0.44 |
| ▸ | HTR4 | Q13639 | 2/20 | 0.43 |
| ▸ | CHRM4 | P08173 | 1/20 | 0.43 |
| ▸ | CHRM5 | P08912 | 1/20 | 0.43 |
| ▸ | ADRA2C | P18825 | 1/20 | 0.43 |
| ▸ | CHRM3 | P20309 | 1/20 | 0.43 |
| ▸ | HTR1D | P28221 | 1/20 | 0.43 |
| ▸ | ADRA1B | P35368 | 1/20 | 0.43 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692407 | 0.92 | KMT2A (0.54) | KMT2AMEN1SLC29A1HTTDRD3 | |
| SCHEMBL6692234 | 0.87 | HTR4 (0.52) | KMT2AMEN1SLC29A1HTTDRD3 | |
| SCHEMBL6692575 | 0.85 | LMNA (0.45) | KMT2AHTTHPGDALDH1A1DRD2 | |
| SCHEMBL6692413 | 0.83 | KMT2A (0.53) | KMT2AMEN1SLC29A1HTTDRD3 | |
| SCHEMBL6692009 | 0.82 | CA12 (0.46) | — | |
| SCHEMBL6703688 | 0.80 | PARP1 (0.49) | KMT2AMEN1SLC29A1DRD3HPGD | |
| SCHEMBL6687434 | 0.80 | HPGD (0.44) | KMT2AMEN1HPGDALDH1A1 | |
| SCHEMBL6697097 | 0.78 | PARP1 (0.42) | KMT2AMEN1HTTHPGDHSD17B10 | |
| SCHEMBL11938971 | 0.77 | DRD2 (0.54) | KMT2AMEN1HPGDPOLBALDH1A1 | |
| SCHEMBL6692746 | 0.76 | CNR2 (0.51) | KMT2AMEN1SLC29A1POLBL3MBTL1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074438-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | claimed |