Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | KMT2A | Q03164 | 3/20 | 0.54 |
| ▸ | MEN1 | O00255 | 2/20 | 0.54 |
| ▸ | HPGD | P15428 | 3/20 | 0.51 |
| ▸ | HSD17B10 | Q99714 | 1/20 | 0.51 |
| ▸ | ALDH1A1 | P00352 | 5/20 | 0.50 |
| ▸ | POLB | P06746 | 1/20 | 0.50 |
| ▸ | CYP2C19 | P33261 | 1/20 | 0.50 |
| ▸ | L3MBTL1 | Q9Y468 | 1/20 | 0.50 |
| ▸ | SLC29A1 | Q99808 | 1/20 | 0.50 |
| ▸ | DRD3 | P35462 | 2/20 | 0.49 |
| ▸ | KDM4E | B2RXH2 | 3/20 | 0.47 |
| ▸ | SMN1; SMN2 | Q16637 | 2/20 | 0.47 |
| ▸ | DRD2 | P14416 | 4/20 | 0.47 |
| ▸ | GAA | P10253 | 2/20 | 0.46 |
| ▸ | MAPT | P10636 | 1/20 | 0.46 |
| ▸ | TSHR | P16473 | 1/20 | 0.46 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.46 |
| ▸ | LMNA | P02545 | 2/20 | 0.46 |
| ▸ | HTT | P42858 | 1/20 | 0.46 |
| ▸ | HTR2A | P28223 | 1/20 | 0.45 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6692232 | 0.92 | KMT2A (0.49) | KMT2AMEN1HPGDHSD17B10ALDH1A1 | |
| SCHEMBL6692413 | 0.87 | KMT2A (0.53) | KMT2AMEN1HPGDHSD17B10ALDH1A1 | |
| SCHEMBL6687434 | 0.86 | HPGD (0.44) | KMT2AMEN1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL6692234 | 0.83 | HTR4 (0.52) | KMT2AMEN1ALDH1A1POLBSLC29A1 | |
| SCHEMBL6703688 | 0.80 | PARP1 (0.49) | KMT2AMEN1HPGDPOLBL3MBTL1 | |
| SCHEMBL6687780 | 0.79 | PARP1 (0.46) | KMT2AMEN1HPGDHSD17B10ALDH1A1 | |
| SCHEMBL6692575 | 0.79 | LMNA (0.45) | KMT2AHPGDALDH1A1DRD2TSHR | |
| SCHEMBL6687439 | 0.77 | HPGD (0.46) | KMT2AMEN1HPGDALDH1A1SMN1; SMN2 | |
| SCHEMBL11938971 | 0.77 | DRD2 (0.54) | KMT2AMEN1HPGDALDH1A1POLB | |
| SCHEMBL3069426 | 0.76 | ALDH1A1 (0.56) | KMT2AMEN1HPGDHSD17B10ALDH1A1 |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 1 patent. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| WO-2004074438-A2 | CCR8 ANTAGONISTS | SMITHKLINE BEECHAM CORPORATION (US) | 2004-09-02 | — | — | WO | claimed |