Predicted protein targets (top 20)
| gene | UniProt | supporting neighbours | confidence | |
|---|---|---|---|---|
| ▸ | LMNA | P02545 | 3/20 | 0.39 |
| ▸ | TP53 | P04637 | 2/20 | 0.36 |
| ▸ | GRIN1 | Q05586 | 2/20 | 0.35 |
| ▸ | GRIN2A | Q12879 | 2/20 | 0.35 |
| ▸ | GRIN2B | Q13224 | 2/20 | 0.35 |
| ▸ | GRIN2D | O15399 | 1/20 | 0.35 |
| ▸ | GRIN3B | O60391 | 1/20 | 0.35 |
| ▸ | GRIN2C | Q14957 | 1/20 | 0.35 |
| ▸ | GRIN3A | Q8TCU5 | 1/20 | 0.35 |
| ▸ | L3MBTL1 | Q9Y468 | 2/20 | 0.35 |
| ▸ | KDM4E | B2RXH2 | 1/20 | 0.35 |
| ▸ | ALOX12 | P18054 | 1/20 | 0.35 |
| ▸ | HTT | P42858 | 1/20 | 0.35 |
| ▸ | TDP1 | Q9NUW8 | 1/20 | 0.35 |
| ▸ | MAPT | P10636 | 1/20 | 0.34 |
| ▸ | BCHE | P06276 | 1/20 | 0.34 |
| ▸ | TSHR | P16473 | 3/20 | 0.34 |
| ▸ | RECQL | P46063 | 2/20 | 0.33 |
| ▸ | ALDH1A1 | P00352 | 1/20 | 0.33 |
| ▸ | GAA | P10253 | 1/20 | 0.33 |
Click a target to see other patent compounds predicted against it — the reverse direction, in place.
Similar compounds — the chemically nearest patent molecules
Nearest neighbours by Morgan-fingerprint cosine across the patent-compound collection, with each neighbour's top predicted target and the predicted targets it shares with this molecule.
| Compound | similarity | top predicted | shared targets | |
|---|---|---|---|---|
| SCHEMBL6690604 | 0.89 | LMNA (0.39) | LMNATP53GRIN1GRIN2AGRIN2B | |
| SCHEMBL6690929 | 0.81 | LMNA (0.40) | LMNATP53GRIN1GRIN2AGRIN2B | |
| SCHEMBL6698691 | 0.79 | HTR2A (0.33) | L3MBTL1MAPTTSHRALDH1A1GAA | |
| SCHEMBL6692267 | 0.78 | LMNA (0.35) | LMNATP53L3MBTL1KDM4EALOX12 | |
| SCHEMBL6697773 | 0.77 | LMNA (0.35) | LMNATP53HRH3 | |
| SCHEMBL6691234 | 0.77 | HTR2A (0.32) | TP53L3MBTL1MAPTTSHRALDH1A1 | |
| SCHEMBL6697961 | 0.73 | MPI (0.38) | KDM4EMAPTTSHRALDH1A1GAA | |
| SCHEMBL6694866 | 0.73 | SMN1; SMN2 (0.38) | LMNATP53L3MBTL1KDM4EHTT | |
| SCHEMBL6693671 | 0.70 | HRH3 (0.38) | LMNAKDM4EALOX12HTTMAPT | |
| SCHEMBL6694327 | 0.69 | RAB9A (0.34) | LMNATP53L3MBTL1MAPTTSHR |
Similarity is cosine over the 2,048-bit Morgan fingerprint (≈ Tanimoto). Identical fingerprints score 1.00.
Patent provenance — the patents this molecule appears in, and who filed them
Claimed or disclosed in 3 patents. claimed = in the patent's claims; disclosed = body only.
| Patent | Title | Assignee | Published | Priority | Filing | Country | Status |
|---|---|---|---|---|---|---|---|
| EP-0869016-B1 | Pneumatic radial tires | BRIDGESTONE CORP (JP) | 2004-03-03 | — | — | EP | disclosed |
| US-6336486-B1 | Pneumatic radical tire having cap base tread | BRIDGESTONE CORPORATION (JP) | 2002-01-08 | — | — | US | disclosed |
| EP-0869016-A2 | Pneumatic radial tires | Bridgestone Corporation (JP) | 1998-10-07 | — | — | EP | disclosed |